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Bring Your Cell Based Assays to Life

The body is made up of nanofibers and now your cell based assays and culture systems can be too. These 3-D environments are more biologically realistic leading to:

Images: A)Confluent cardiomyocytes cultured on aligned nanofibers. B)Stem cells cultured on random nanofibers. C)Interactive Microenvironment System (IMEMS)cross section.

  • more effective biomedical research.
  • earlier breakthroughs.
  • faster and cheaper time to market for drug development.
  • improved stem cell expansion rates.

Nanofiber Solutions Options

  • Mimic aligned and oriented parts of the body such as white matter within the brain, the central nervous system, cardiac tissue, skeletal muscle, and many others.
  • Help control differentiation of stem cells into the desired cell type by providing the appropriate physical cues for cardiomyocytes, neurons, myoblasts, etc.
  • Provide an ideal substrate for high-throughput, real-time imaging and quantification of cell migration and is much more physiologically relevant than typical 'scratch assays
  • Mimic the nanofibrous extracellular matrix found throughout the body
  • Provide a substrate for adherent stem cell expansion that produces higher expansion rates while maintaining stem cell pluripotency Increased surface area which facilitates culturing higher cell numbers which can result in higher production levels of monoclonal antibodies, cytokines, etc.
  • Increased surface area which facilitates culturing higher cell numbers  which can result in higher production levels of monoclonal antibodies, cytokines, etc.

 

  • Allows co-culture of several different cell types for enhanced interaction and cellular response.
  •  Cells have chemical communication, but not physical contact which allows easy post-analysis of each cell type.
  •  Each layer within the IMEMS allows for high-resolution imaging of the cells after the culture period
Note: nanofibers solutions are integrated into standard multi-well cell culture dishes and can be easily scaled up for larger bioreactor systems.
3-D Aligned Nanofiber Solutions
Plates, Chambers, Dishes and Inserts
3-D Random Nanofiber Solutions
Plates, Chambers, Dishes and Inserts
Culturing Protocols for 3D Nanofiber Solutions
Coatings Seeding, Culturing, Viability, Toxicity and Imaging Protocols

Aligned Scaffolds, Randomly Oriented Scaffolds and Interactive Microenvironment System (IMEMS).

  
3-D Aligned Nanofiber Solutions
Plates, Chambers, Dishes and Inserts
3-D Random Nanofiber Solutions
Plates, Chambers, Dishes and Inserts
3-D Nanofibers Interactive Microenvironment System (IMEMS)
Designed for 3-D Cell Co-culturing
Culturing Protocols for 3D Nanofiber Solutions
Coatings Seeding, Culturing, Viability, Toxicity and Imaging Protocols