Human Osteoblasts-New

Potent, Pure and Stable Osteoblasts

We continue to work with our partners to develop pure and stable cultures of primary human cells derived from our commercially available eSC and UCB derived stem cells. Working with Dr. Jim Musick of Vitro Biopharma, we are pleased to be one of the first to  human osteoblasts.

Osteoblasts are mononucleated cells that are responsible for the synthesis and mineralization of bone during initial bone formation and later bone remodeling. These cells are use for the study of osteogenesis and also focal bone erosion in rheumatoid arthritis.

Images: (A) Mature osteoblasts stained positive for Alizarin red with numerous areas of associated mineralized matrix. Phase contrast image at 200 x. (B) FITC image of mature osteoblast. Most individual cells of the osteoblast are fluorescent, indicating efficient transfer of FITC from MSCs to osteoblasts during differentiation.

All lots of our osteoblast cells are cultured and characterized in house (includes testing  by PCR methods for known viral such as contaminants and mycoplasma). The vials contain minimal amounts of non-differentiated MSCs (<10%).