hMPro Mesenchymal Stem Progeitors are derived from human embryonic cell line, H9 (WA09). Cells are >80% CD90, CD105, CD166 and CD73 positive and <5% Oct4 positive.

These multipotent cells have the capabilities to form osteogenic and chondrogenic, but not adipogenic lineages. The have the ability to remodel and contract collagen I lattice constructs to an equivalent degree as keloid fibroblasts and were induced to express α-smooth muscle actin when exposed to transforming growth factor (TGF)-β1, but not platelet derived growth factor-B (PDGF-B).

hMProTM (MPCs) are osteogenic and chondrogenic, but not adipogenic. hMPro MPCs  and bone marrow–derived human MSC were subject to MSC three-lineage differentiation protocols. For negative controls, both cell types were cultured in normal growth media. (A) Osteogenic conditions and von Kossa staining. (B) Chondrogenic conditions and Alcian blue staining. (C) Adipogenic conditions and Oil Red-O staining. Images are representative of WA09 (n = 3) and BG01 (n = 2). (10 × magnification). (doi:10.1089/ten.tea.2008.0351).

They are ideal for use in tissue engineering and regenerative medicine and for providing a highly reproducible cell source for adult-like progenitor cells. Note: they can be passaged up to 10X.

NameCatalog #TypeSpeciesApplicationsSizePrice
hMPro hMPCsHN60003Primary Cells1,000,000 cells$575