Product Details
Catalog Number: RA24446
Applications: IHC
Type: Rabbit IgG
Immunogen: 5-HTP coupled to bovine serum albumin (BSA) with paraformaldehyde.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Rat
Entrez: 551
UniProt: P01185
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$302.50Add to Cart

5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor as well as metabolic intermediate in the biosynthesis of the neurotransmitters serotonin and melatonin from tryptophan. 5-Hydroxytryptophan is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT) by the enzyme aromatic-L-amino-acid decarboxylase with the help of vitamin B6.[4] This reaction occurs both in nervous tissue and in the liver.5-HTP crosses the blood-brain barrier,[6] while 5-HT does not.

Since 5-HTP incresease levels of serotonin, it is used to treat depression, sleep disorders and pain.