Neurons, Astrocytes, Schwann Cells, Microglia, & Other CNS Cells

Catalog Number: HNC001

1. Fumiaki Shima and Tomomi Makino. (2022). Construction of Brain-Like Spheroids Containing Endothelial Tubular Networks by an Adhesive Culture System. Biochemical and Biophysical Research Communications. doi: 10.1016/j.bbrc.2022.07.063
2. Wei-Bin Shen, James Logue, Penghua Yang, Lauren Baracco, Montasir Elahi, E. Albert Reece, Bingbing Wang, Ling Li, Thomas G. Blanchard, Zhe Han, Matthew B Frieman, Robert A. Rissman, and Peixin Yang. (2022). SARS-CoV-2 Invades Cognitive Centers of the Brain and Induces Alzheimer’s-Like Neuropathology. bioRxiv. doi: 10.1101/2022.01.31.478476
3. Sabine Heitzeneder, Kristopher R. Bosse, Zhongyu Zhu, Doncho Zhelev, Robbie G. Majzner, Molly T. Radosevich, Shaurya Dhingra, Elena Sotillo, Samantha Buongervino, Guillem Pascual-Pasto, Emily Garrigan, Peng Xu, Jing Huang, Benjamin Salzer, Alberto Delaidelli, Swetha Raman, Hong Cui, Benjamin Martinez, and Crystal L. Mackall. (2021). GPC2-CAR T Cells Tuned for Low Antigen Density Mediate Potent Activity Against Neuroblastoma Without Toxicity. Cancer Cell, 40, 1–17. doi: 10.1016/j.ccell.2021.12.005
4. Alexzander Asea, Punit Kaur, Alexander Panossian, Karl Georg Wikman. (2013). Evaluation of molecular chaperons Hsp72 and neuropeptide Y as characteristic markers of adaptogenic activity of plant extracts. Phytomedicine, doi: 10.1016/j.phymed.2013.07.001

Product Patent Application

1. Imadul Islam, Rabih O. Al-Kaysi, Mohamed Boudjelal, Rizwan Ali, Atef Nehdi, and Bandar Alghanem. (2020). Anticancer 1,3-Dioxane-4,6-Dione Derivatives and Method of Combinatorial Synthesis Thereof.  United States Patent Application 20200290975

Catalog Number: HMP202

1. Yvonne Adams, Anne Skovsbo Clausen, Peter Østrup Jensen, Malin Lager, Peter Wilhelmsson, Anna J. Henningson, Per-Eric Lindgren, Daniel Faurholt-Jepsen, Helene Mens, Peter Kraiczy, Kasper Nørskov Kragh, Thomas Bjarnsholt, Andreas Kjaer, Anne-Mette Lebech, and Anja R. Jensen. (2022). 3D Blood-Brain Barrier-Organoids as a Model for Lyme Neuroborreliosis Highlighting Genospecies Dependent Organotropism. iScience. doi: 10.1016/j.isci.2022.105838
2. Elizabeth Evans, Vikas Mishra, Crystal Mallow, Elaine Gersz, Leslie Balch, Alan Howell, Christine Reilly, Ernest Smith, Terrence Fisher, and Maurice Zauderer. (2022). Semaphorin 4D is Upregulated in Neurons of Diseased Brains and Triggers Astrocyte Reactivity. Journal of Neuroinflammation, 19:200. doi: 10.1186/s12974-022-02509-8
3. Sabine Heitzeneder, Kristopher R. Bosse, Zhongyu Zhu, Doncho Zhelev, Robbie G. Majzner, Molly T. Radosevich, Shaurya Dhingra, Elena Sotillo, Samantha Buongervino, Guillem Pascual-Pasto, Emily Garrigan, Peng Xu, Jing Huang, Benjamin Salzer, Alberto Delaidelli, Swetha Raman, Hong Cui, Benjamin Martinez, and Crystal L. Mackall. (2021). GPC2-CAR T Cells Tuned for Low Antigen Density Mediate Potent Activity Against Neuroblastoma Without Toxicity.  Cancer Cell, 40, 1–17. doi: 10.1016/j.ccell.2021.12.005
4. Sorel Kurbegovic, Karina Juhl, Kasper Kildegaard Sorensen, Julie Leth, Gro Linno Willemoe, Anders Christensen, Yvonne Adams, Anja Ramstedt Jensen, Christian Von Buchwald, Jane Skjoth-Rasmussen, Michael Ploug, Knud J. Jensen, Andreas Kjaer. (2021). IRDye800CW Labeled uPAR-Targeting Peptide for Fluorescence-Guided Glioblastoma Surgery: Preclinical Studies in Orthotopic Xenografts. Theranostics, 11(15): 7159-7174. doi: 10.7150/thno.49787
5. Yvonne Adams, Rebecca W. Olsen, Anja Bengtsson, Nanna Dalgaard, Mykola Zdioruk, Sanghamitra Satpathi, Prativa K. Behera, Praveen K. Sahu, Sean E. Lawler, Klaus Qvortrup, Samuel C. Wassmer, and Anja T.R. Jensen. (2021). Plasmodium Falciparum Erythrocyte Membrane Protein 1 Variants Induce Cell Swelling and Disrupt the Blood–Brain Barrier in Cerebral Malaria. Journal of Experimental Medicine, 218 (3). doi: 10.1084/jem.20201266
6. Yang Wu, Yan Li, Liangqing Zheng, Pengcheng Wang, Yan liu, Yongning Wu, ZhiYong Gonga (2019). The neurotoxicity of Nε-(carboxymethyl)lysine in food processing by a study based on animal and organotypic cell culture. Ecotoxicology and Environmental Safety. https://doi.org/10.1016/j.ecoenv.2019.110077
7. Ece Bayir, M. Mert Celtikoglu, Aylin Sendemir. (2018). The use of bacterial cellulose as a basement membrane improves the plausibility of the static in vitro blood-brain barrier model. International Journal of  Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.12.257
8. Anders Lundin, Louise Delsing, Maryam Clausen, Piero Ricchiuto, José Sanchez, Alan Sabirsh, Mei Ding, Jane Synnergren, Henrik Zetterberg, Gabriella Brolén, Ryan Hicks, Anna Herland, and Anna Falk. (2018). Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models. Stem Cell Reports. DOI: https://doi.org/10.1016/j.stemcr.2018.01.021

Catalog Number: HMP303

1. Seung Min Shin, Francie Moehring, Brandon Itson-Zoske, Fan Fan, Cheryl L. Stucky, Quinn H. Hogan, and Hongwei Yu. (2021). Piezo2 Mechanosensitive Ion Channel is Located to Sensory Neurons and Non-Neuronal Cells in Rat Peripheral Sensory Pathway: Implications in Pain. bioRxiv. doi: 10.1101/2021.01.20.427483

Catalog Number: HBMCs001

1. Li Yao, Jacques Blasi, Teresa Shippy, and Ryan Brice. (2023). Transcriptomic Analysis Reveals the Immune Response of Human Microglia to a Soy Protein and Collagen Hybrid Bioscaffold. Heliyon, 9(2): e13352. doi: 10.1016/j.heliyon.2023.e13352

Catalog Number: HEC02

1. Eunnyung Bae, Ping Huang, Gaёlle Müller-Greven, Dolores Hambardzumyan, Andrew Edward Sloan, Amy S. Nowacki, Nicholas Marko, Cathleen R. Carlin, and Candece L. Gladson. (2022). Integrin α3β1 Promotes Vessel Formation of Glioblastoma-Associated Endothelial Cells through Calcium-Mediated Macropinocytosis and Lysosomal Exocytosis. Nature Communications, 13:4268. doi: 10.1038/s41467-022-31981-2
2. Tao Jin, Gong Chen, Qingzhu An, Xuanfeng Qin, Yuanyuan Hu, Yan Yan, Jia Hu, Bing Zhou, and Bing Leng. (2022). miR-139-5p Suppresses Proliferation and Angiogenesis of Intracranial Aneurysm via FGB. Journal of Healthcare Engineering. doi: 10.1155/2022/5824327
3. Guetchyn Millien, Huaixing Wang, Zongxiu Zhang, Dan L Alkon, and Jarin Hongpaisan. (2022). PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer’s Disease Hippocampus. Frontiers in Aging Neuroscience. doi: 10.3389/fnagi.2022.836634
4. Pasquale Mone, Jessica Gambardella, Antonella Pansini, Antonio de Donato, Giuseppe Martinelli, Eugenio Boccalone, Alessandro Matarese, Salvatore Frullone, and Gaetano Santulli. (2021). Cognitive Impairment in Frail Hypertensive Elderly Patients: Role of Hyperglycemia. Cells, 10(8), 2115. doi: 10.3390/cells10082115
5. Pasquale Mone, Jessica Gambardella, Xujun Wang, Stanislovas S. Jankauskas, Alessandro Matarese, and Gaetano Santulli. (2021). miR-24 Targets the Transmembrane Glycoprotein Neuropilin-1 in Human Brain Microvascular Endothelial Cells. Non-coding RNA, 7, 9. doi: 10.3390/ncrna7010009
6. Concetta Scimone, Luigi Donato, Simona Alibrandi, Teresa Esposito, Concetta Alafaci, Rosalia D'Angelo, and Antonina Sidoti. (2020). Transcriptome Analysis Provides New Molecular Signatures in Sporadic Cerebral Cavernous Malformation Endothelial Cells. Molecular Basis of Disease, 1866(12). doi: 10.1016/j.bbadis.2020.165956
7. Yang Wu, Yan Li, Liangqing Zheng, Pengcheng Wang, Yan liu, Yongning Wu, ZhiYong Gonga (2019). The neurotoxicity of Nε-(carboxymethyl)lysine in food processing by a study based on animal and organotypic cell culture. Ecotoxicology and Environmental Safety. https://doi.org/10.1016/j.ecoenv.2019.110077
8. Hyun-Jung Choi, Na-Eun Kim, Il Kwon, Dukhwan Choi, Jayoung Kim, Ji Hoe Heo. (2019). Fc-saxatilin inhibits VEGF-induced permeability by regulating claudin-5 expression in human brain microvascular endothelial cells. Microvascular Research. DOI: https://doi.org/10.1016/j.mvr.2019.103953
9. Larry W. Hunter, Muthuvel Jayachandran and Virginia M. Miller (2019). Sex differences in the expression of cell adhesion molecules on microvesicles derived from cultured human brain microvascular endothelial cells treated with inflammatory and thrombotic stimuli. Biology of Sex Differences 201910:26. https://doi.org/10.1186/s13293-019-0241-y
10. Ece Bayir, M. Mert Celtikoglu, Aylin Sendemir. (2018). The use of bacterial cellulose as a basement membrane improves the plausibility of the static in vitro blood-brain barrier model. International Journal of  Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.12.257
11. Shavali Shaik, Bridget Kennis, Shinji Maegawa, Keri Schadler, Yang Yanwen, Keri Callegari, Rishi R. Lulla, Stewart Goldman, Javad Nazarian, Veena Rajaram, Jason Fangusaro, and Vidya Gopalakrishnan. (2018). REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature. Oncotarget. 2018 Jan 12; 9(4): 5233–5250. doi: 10.18632/oncotarget.23750
12. Baoli Hu, Qianghu Wang, Y. Alan Wang, Sujun Hua, Charles-Etienne Gabriel Sauvé, Derrick Ong, Zheng D.Lan, Qing Chang, Yan Wing Ho, Marta Moreno Monasterio, Xin Lu, Y iZhong, Jianhua Zhang, Pingna Deng, Zhi Tan, Guocan Wang, Wen-Ting Liao, Lynda J. Corley, Haiyan Yan, Junxia Zhang, Yongping You, Ning Liu, Linbo Cai, Gaetano Finocchiaro, Joanna J. Phillips, Mitchel S. Berger, Denise J. Spring, Jian Hu, Erik P. Sulman, Gregory N. Fuller, Lynda Chin, Roeland G. W. Verhaak, and Ronald A. DePinho. (2016). Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 167, 1281–1295. http://dx.doi.org/10.1016/j.cell.2016.10.039

Product Patent Application

1. Kenneth M. Rosen, Matthew D. Abbinanti, Joerg Ruschel, Lisa Mckerracher, and Lisa Bond Moritz. (2020). Rho Kinase Inhibitor BA-1049 (R) and Active Metabolites Thereof. United States Patent Application 20200199105

Catalog Number: HMP104

1. Yvonne Adams, Anne Skovsbo Clausen, Peter Østrup Jensen, Malin Lager, Peter Wilhelmsson, Anna J. Henningson, Per-Eric Lindgren, Daniel Faurholt-Jepsen, Helene Mens, Peter Kraiczy, Kasper Nørskov Kragh, Thomas Bjarnsholt, Andreas Kjaer, Anne-Mette Lebech, and Anja R. Jensen. (2022). 3D Blood-Brain Barrier-Organoids as a Model for Lyme Neuroborreliosis Highlighting Genospecies Dependent Organotropism. iScience. doi: 10.1016/j.isci.2022.105838
2. Sorel Kurbegovic, Karina Juhl, Kasper Kildegaard Sorensen, Julie Leth, Gro Linno Willemoe, Anders Christensen, Yvonne Adams, Anja Ramstedt Jensen, Christian Von Buchwald, Jane Skjoth-Rasmussen, Michael Ploug, Knud J. Jensen, Andreas Kjaer. (2021). IRDye800CW Labeled uPAR-Targeting Peptide for Fluorescence-Guided Glioblastoma Surgery: Preclinical Studies in Orthotopic Xenografts. Theranostics, 11(15): 7159-7174. doi: 10.7150/thno.49787
3. Yvonne Adams, Rebecca W. Olsen, Anja Bengtsson, Nanna Dalgaard, Mykola Zdioruk, Sanghamitra Satpathi, Prativa K. Behera, Praveen K. Sahu, Sean E. Lawler, Klaus Qvortrup, Samuel C. Wassmer, and Anja T.R. Jensen. (2021). Plasmodium Falciparum Erythrocyte Membrane Protein 1 Variants Induce Cell Swelling and Disrupt the Blood–Brain Barrier in Cerebral Malaria. Journal of Experimental Medicine, 218 (3). doi: 10.1084/jem.20201266
4. Ece Bayir, M. Mert Celtikoglu, Aylin Sendemir. (2018). The use of bacterial cellulose as a basement membrane improves the plausibility of the static in vitro blood-brain barrier model. International Journal of  Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.12.257

Catalog Numbers: HEC09

1. Yong Yao Xu, Michael Twarog, Ning Li, Angela Banks, Josh Schustak, Yi Bao, Qian Huang, and Quintus Medley. (2022). Zinc Transport from the Endoplasmic Reticulum to the Cytoplasm via Zip7 is Necessary for Barrier Dysfunction Mediated by Inflammatory Signaling in RPE Cells. PLoS ONE 17(7): e0271656. doi: 10.1371/journal.pone.0271656
2. A. Gericke, K. Suminska-Jasinska, and A. Breborowicz. (2021). Sulodexide Reduces Glucose Induced Senescence in Human Retinal Endothelial Cells. Scientific Reports, 11:11532. doi: 10.1038/s41598-021-90987-w
3. Fei Cai, Huanzong Jiang, Yan Li, Qin Li, and Chao Yang. (2021). Up-Regulation of Long Non-Coding RNA SNHG16 Promotes Diabetes-Related Retinal Microvascular Endothelial Cell Dysfunction via Activating NF-κB and PI3K/AKT Pathways. Molecular Therapy: Nucleic Acid. doi: 10.1016/j.omtn.2021.01.035
4. A. P. Da Cunha, Q. Zhang, M. Prentiss, X. Q. Wu, V. Kainz, Y. Y. Xu, J. Vrouvlianis, H. Li, N. Rangaswamy, B. Leehy, T. L. McGee, C. L. Bell, C. E. Bigelow, V. Kansara, Q. Medley, Q. Huang & H. Y. Wu. The Hierarchy of Proinflammatory Cytokines in Ocular Inflammation. Current Eye Research, Volume 43, 2018 - Issue 4 Published Online: 04 Dec 2017
5. Odunayo O. Mugisho, Colin R. Green, Jie Zhang, Nicolette Binz, Monica L. Acosta, Elizabeth Rakoczy and Ilva D. Rupentha. (2017). Immunohistochemical Characterization of Connexin43 Expression in a Mouse Model of Diabetic Retinopathy and in Human Donor Retinas. Int. J. Mol. Sci. doi: 10.3390/ijms18122567
6. Michael Anthony Ruiz, Biao Feng, and Subrata Chakrabarti. (2015). Polycomb Repressive Complex 2 Regulates MiR-200b in Retinal Endothelial Cells: Potential Relevance in Diabetic Retinopathy. PLoS One.10(4): e0123987. doi: 10.1371/journal.pone.0123987.

Product Patent Application

1. Pam Tsuruda, Jill Hopkins, Harry Sweigard, Yan Poon, Jamie Dananberg, Daniel Marquess, and Nathaniel David. (2020). Methods of Inhibiting Pathological Angiogenesis.  United States Patent Application 20200253991

Catalog Number: HMP101

1. Paul P. Partyka, Ying Jin, Julien Bouyer, Angelica DaSilva, George A. Godsey, Robert G. Nagele, Itzhak Fischer & Peter A. Galie (2019). Harnessing neurovascular interaction to guide axon growth. Scientific Reports volume 9, Article number: 2190. https://doi.org/10.1038/s41598-019-38558-y

1. Juan Pablo Lezana, Shachar Y. Dagan, Ari Robinson, Ron S. Goldstein, Mike Fainzilber, Francisca C. Bronfman, and Miguel Bronfman. (2015). Axonal pparγ promotes neuronal regeneration after injury. Developmental Neurobiology, doi:10.1002/dneu.22353.
2. Yuji Kaneko, Hideki Shojo, Jack Burns, Meaghan Staples, Naoki Tajiri, Cesar V. Borlongan. (2013). DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway, Neurobiology of Disease, doi: 10.1016/j.nbd.2013.09.007.
3. Xiufang Guo, Severo Spradling, Maria Stancescu, Stephen Lambert, James J. Hickman. (2013). Derivation of sensory neurons and neural crest stem cells from human neural progenitor hNP1. Biomaterials, doi: 10.1016/j.biomaterials.2013.02.061
4. Jenica D. Tapocik, Estelle Barbier, Meghan Flanigan, Matthew Solomon, Alexandra Pincus, Andrew Pilling, Hui Sun, Jesse R. Schank, Courtney King, and Markus Heilig. (2014). microRNA-206 in Rat Medial Prefrontal Cortex Regulates BDNF Expression and Alcohol Drinking. The Journal of Neuroscience, doi: 10.1523/JNEUROSCI.3707-13.2014.
5. Sujoy K. Dhara, Brian A. Gerwe, Anirban Majumder, Mahesh C. Dodla, Nolan L. Boyd, David W. Machacek, Kowser Hasneen, Steven L. Stice. (2009). Genetic Manipulation of Neural Progenitors Derived from Human Embryonic Stem Cells. TISSUE ENGINEERING: Part A. Volume 15, Number 00, doi: 10.1089=ten.tea.2009.0155
6. Adam D. Bachstetter, Jennifer Jernberg, Andrea Schlunk, Jennifer L. Vila, Charles Hudson, Michael J. Cole, R. Douglas Shytle, Jun Tan, Paul R. Sanberg, Cyndy D. Sanberg, Cesario Borlongan, Yuji Kaneko, Naoki Tajiri, Carmelina Gemma, Paula C. Bickford. (2010). Spirulina Promotes Stem Cell Genesis and Protects against LPS Induced Declines in Neural Stem Cell Proliferation. PLoS ONE 5(5): e10496, doi: 10.1371/journal.pone.0010496.