Fibroblasts, CAFs, & Cancer Cells

Catalog Number: CAF110-IM

1. I. Tsimafeyeu, P. Makhov, D. Ovcharenko, J. Smith, Y. Khochenkova, A. Olshanskaya, and D. Khochenkov. (2024). A Novel Anti-FGFR1 Monoclonal Antibody OM-RCA-01 Exhibits Potent Antitumor Activity and Enhances the Efficacy of Immune Checkpoint Inhibitors in Lung Cancer Models. Immuno-Oncology and Technology, 23, 100725. doi: 10.1016/j.iotech.2024.100725

Catalog Number: CAF115

1. Astha Lamichhane, Prasiddha Guragain, Jacob Heiss, Pouria Rafsanjani Nejad, Anju Rana Magar, Nicholas Ciavattone, Seema Agrawal, Gary D Luker, and Hossein Tavana. (2025). Targeting CAFs-Mediated Stromal Signaling in a Patient-Derived Organotypic Colorectal Tumor Model. Molecular Cancer Therapeutics. doi: 10.1158/1535-7163.MCT-24-0756
2. Alexandre Dufour, Lucie Essayan, Celine Thomann, Emma Petiot, Isabelle Gay, Magali Barbaroux, and Christophe Marquette. (2024). Confined Bioprinting and Culture in Inflatable Bioreactor for the Sterile Bioproduction of Tissues and Organs. Scientific Reports, 14:11003. doi: 10.1038/s41598-024-60382-2
3. Pujiang Shi, Tianle Huang, Hong Kit Lim, Chiew Kei Tan, Jong-Min Lee, and Chor Yong Tay. (2024). Transforming Electronic Plastics into Bioadaptive 3D Porous Construct for Advanced Cell Culture Applications. Resources, Conservation and Recycling, 200:107297. doi: 10.1016/j.resconrec.2023.107297
4. Yuanguo Wang, Xianghu Wang, Bing Bai, Aurpita Shaha, Xipu He, Yingzi He, Zhenqing Ye, Vijay Shah, and Ningling Kang. (2024). Targeting Src SH3 Domain-Mediated Glycolysis of Hepatic Stellate Cells Suppresses Transcriptome, Myofibroblastic Activation, and Colorectal Liver Metastasis. Hepatology. doi: 10.1097/HEP.0000000000000763
5. Verena Damiani, Maria Concetta Cufaro, Maurine Fucito, Beatrice Dufrusine, Claudia Rossi, Piero Del Boccio, Luca Federici, Maria Caterina Turco, Michele Sallese, Damiana Pieragostino, and Vincenzo De Laurenzi. (2022). Proteomics Approach Highlights Early Changes in Human Fibroblasts-Pancreatic Ductal Adenocarcinoma Cells Crosstalk. Cells, 11, 1160. doi: 10.3390/cells11071160
6. Bashar Emon, Zhengwei Li, Md Saddam H. Joy, Umnia Doha, Farhad Kosari, and M. Taher A. Saif. (2021). A Novel Method for Sensor-Based Quantification of Single/Multicellular Force Dynamics and Stiffening in 3D Matrices. Science Advances, 7(15). doi: 10.1126/sciadv.abf2629
7. Huan Cao, Hong Sheng Cheng, Jun Kit Wang, Nguan Soon Tan, and Chor Yong Tay. (2020). A 3D Physio-Mimetic Interpenetrating Network-Based Platform to Decode the Pro and Anti-Tumorigenic Properties of Cancer-Associated Fibroblasts. Acto Biomaterialia. doi: 10.1016/j.actbio.2021.03.037
8. Bashar Emon, Zhengwei Li, Md Saddam Hossain Joy, Umnia Doha, Farhad Kosari, and M Taher A Saif. (2020). A Novel Method for Sensor-Based Quantification of Single/Multi-Cellular Traction Dynamics and Remodeling in 3D Matrices. bioRxiv. doi: 10.1101/2020.09.24.311647
9. Martin Nurmik, Pit Ullmann, Fabien Rodriguez, Serge Haan, Elisabeth Letellier. In search of definitions: Cancer-associated fibroblasts and their markers. doi: 10.1002/ijc.32193

Product Patent Application

1. So Yeon Kim, Hyeran Gwak, Eun Gyeong Yang. (2020). Composition and Kit for Differentiating Cancer Associated Fibroblasts into Macrophages, and Method of Using the Same.  United States Patent Application 20200248141

Catalog Number: CAF118

1. Pratibha Malhotra, Jordan Fyfe, Aikaterini Emmanouilidi, Ilaria Casari, Natalie A. Mellett, Kevin Huynh, Marina Pajic, David W. Greening, Peter J. Meikle, and Marco Falasca. (2025). Oncogenic Small extracellular Vesicles Enriched in Sphingosine-1-Phosphate Play a Crucial Role in Pancreatic Cancer Progression. Cellular Signalling, 111775. doi: 10.1016/j.cellsig.2025.111775
2. Jian-Ping Yang, Nikhil Nitin Kulkarni, Masashi Yamaji, Tsubasa Shiraishi, Thang Pham, Han Do, Nicole Aiello, Michael Shaw, Toshihiro Nakamura, Akiko Abiru, Narender R. Gavva, and Shane R. Horman. (2024). Unveiling Immune Cell Response Disparities in Human Primary Cancer-Associated Fibroblasts Between Two- And Three-Dimensional Cultures. PloS one, 19(12), e0314227. doi: 10.1371/journal.pone.0314227
3. Hao-Chien Hung, Chang-Gung, Tsui-Lien Mao, Ming-Huei Fan, Guan-Zhi Huang, and Chao-Lien Liu. (2023). Enhancement of Tumorigenicity, Spheroid Niche, and Drug Resistance of Pancreatic Cancer Cells in Three-Dimensional Culture System. Research Square. doi: 10.21203/rs.3.rs-2889040/v1
4. Georgia Papaparaskeva, Maria Louca, Chrysovalantis Voutouri, Eugenia Tanasa, Triantafyllos Stylianopoulos, and Theodora Krasia-Christoforou. (2020). Amalgamated Fiber/Hydrogel Composites Based on Semi-Interpenetrating Polymer Networks and Electrospun Nanocomposite Fibrous Mats. European Polymer Journal, 140:110041. doi: 10.1016/j.eurpolymj.2020.110041
5. Aleksandra Adamska, Alice Domenichini, Emily Capone, Verena Damiani, Begum Gokcen Akkaya, Kenneth J. Linton, Pierluigi Di Sebastiano, Xi Chen, Adam B. Keeton, Veronica Ramirez-Alcantara, Yulia Maxuitenko, Gary A. Piazza, Vicenzo De Laurenzi, Gianluca Sala, and Marco Falasca. (2019). Pharmacological Inhibition of ABCC3 Slows Tumour Progression in Animal Models of Pancreatic Cancer. Journal of Experimental and Clinical Cancer Research, 38:312. doi: 10.1186/s13046-019-1308-7

6. Andreas Stylianou, Vasiliki Gkretsi, Maria Louca, Lefteris C. Zacharia, and Triantafyllos Stylianopoulos (2019). Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts. J. R. Soc. Interface 16: 20190226. http://dx.doi.org/10.1098/rsif.2019.0226

7. Stylianou, Andreas & Gkretsi, Vasiliki & Stylianopoulos, Triantafyllos. (2018). Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion. Biochimica et biophysica acta. 1862. 10.1016/j.bbagen.2018.02.009.

8. Zenobia D'Costa, Keaton Jones, Abul Azad, Ruud van Stiphout, Su Y Lim, Ana L Gomes, Paul Kinchesh, Sean C Smart, W. Gillies McKenna, Francesca M Buffa, Owen J. Sansom, Ruth J. Muschel, Eric O'Neill and Emmanouil Fokas. (2017). Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer. doi: 10.1158/0008-5472.CAN-16-2833

Catalog Number: CAF117

1. Yi Yuan. (2024). Modulating Tumor Immunity to Suppress Tumor Progression in Non-Small Cell Lung Cancer. Georgia State University, Doctoral Dissertation.
2. Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, Christelle M. Colin, Jennifer Y. Lee, Matthew W. Martin, Xiaozhang Zheng, Domenico Coppola, and Srikumar Chellappan. (2020). Novel HDAC11 Inhibitors Suppress Lung Adenocarcinoma Stem Cell Self-Renewal and Overcome Drug Resistance by Suppressing Sox2. Scientific Reports, 10:4722. doi: 10.1038/s41598-020-61295-6

Catalog Numbers: CAF116

1. Sunil Singh. (2021). Engineered Organotypic Breast Tumor Model for Mechanistic Studies of Tumor-Stromal Interactions and Drug Discovery. University of Akron, Doctoral Dissertation
2. Luis P. Ferreira, Vitor M. Gaspar, Maria V. Monteiro, Bruno Freitas, Nuno J.O. Silva, and Joao F. Mano. (2020). Screening of Dual Chemo-Photothermal Cellular Nanotherapies in Organotypic Breast Cancer 3D Spheroids. Journal of Controlled Release. doi: 10.1016/j.jconrel.2020.12.054

Catalog Number: HPF001

1. Gareth C.G. Davies, Neesha Dedi, Paul S. Jones, Lara Kevorkian, David McMillan, Cristina Ottone, Monika-Sarah E.D. Schulze, Anthony Scott-Tucker, Roohi Tewari, Shauna West, Michael Wright, and Tania F. Rowley. (2023). Discovery of Ginisortamab, a Potent and Novel Anti-Gremlin-1 Antibody in Clinical Development for the Treatment of Cancer.  mAbs, 15:1, 2289681. doi: 10.1080/19420862.2023.2289681

Catalog Number: TR01-GFP

1. Augustino V. Scorzo, Caleb Y. Kwon, Rendall R. Strawbridge, P. Jack Hoopes, David W. Roberts, and Scott C. Davis. (2025). Elucidating the Effect of Tumor and Background Region-of-Interest Selection on the Performance Metrics Used to Assess Fluorescence Imaging. Journal of Biomedical Optics, 30(4), 046004. doi: 10.1117/1.JBO.30.4.046004
2. Augustino V. Scorzo, Brook K. Byrd, Caleb Y. Kwon, Rendall R. Strawbridge, Kimberley S. Samkoe, P. Jack Hoopes, Keith D. Paulsen, David W. Roberts, Scott C. Davis. (2024). Whole-Body Fluorescence Cryotomography Identifies a Fast-Acting, High-Contrast, Durable Contrast Agent for Fluorescence-Guided Surgery. Theranostics, 14(17):6426–6445. doi: 10.7150/thno.100802

Catalog Number: WI001

1. Alyaa Farid, Adham Mohamed, Ayten Ahmed, Farah Mehanny, and Gehan Safwat. (2024). Preparation of Bee Venom-Loaded Chitosan Nanoparticles for Treatment of Streptozotocin-Induced Diabetes in Male Sprague Dawley Rats. Beni-Suef University Journal of Basic and Applied Sciences, 13(97). doi: 10.1186/s43088-024-00557-y

Catalog Number: SF001

1. Duy D. Nguyen, William F. Hooper, Weisi Liu, Timothy R. Chu, Heather Geiger, Jennifer M. Shelton, Minita Shah, Zoe R. Goldstein, Lara Winterkorn, Adrienne Helland, Michael Sigouros, Jyothi Manohar, Jenna Moyer, Majd Al Assaad, Alissa Semaan, Sandra Cohen, Florencia Madorsky Rowdo, David Wilkes, Mohamed Osman, Rahul R. Singh, Andrea Sboner, Henkel L. Valentine, Phillip Abbosh, Scott T. Tagawa, David M. Nanus, Jones T. Nauseef, Cora N. Sternberg, Ana M. Molina, Douglas Scherr, Giorgio Inghirami, Juan Miguel Mosquera, Olivier Elemento, Nicolas Robine, and Bishoy M. Faltas. (2024). The Interplay of Mutagenesis and ecDNA Shapes Urothelial Cancer Evolution. Nature. doi: 10.1038/s41586-024-07955-3