Carcinoma associated fibroblasts (CAFs) have recently been implicated in important aspects of epithelial solid tumor biology such as neoplastic progression, tumor growth, angiogenesis, and metastasis. Human Lung Adenocarcinoma CAFs are isolated from human lung tumor tissue. Cells are grown in T75 tissue culture flasks. Prior to shipping, cells at passage 1 are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1,000,000 cells.
Human Lung Adenocarcinoma CAFs can be used for the assay of cell-cell interaction, adhesion, PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications. Cells can be expanded for 3-5 passages.
Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.
|AlphaBioCoat Solution||AC001||20 ml|
|CAF Growth Media||CAFM03||500 ml|
|Cell Detachment Solution||ADF001||50 ml|
|Stem Cell Complete Low Serum Media||CAFM01||500 ml|
|Stem Cell Complete Media||CAFM02||500 ml|
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- Product Publications
- Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, Christelle M. Colin, Jennifer Y. Lee, Matthew W. Martin, Xiaozhang Zheng, Domenico Coppola, and Srikumar Chellappan. (2020). Novel HDAC11 Inhibitors Suppress Lung Adenocarcinoma Stem Cell Self-Renewal and Overcome Drug Resistance by Suppressing Sox2. Scientific Reports, 10:4722. doi: 10.1038/s41598-020-61295-6
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