When Neuromics opened in 2005, we solely provided neuroscience research antibodies. While we have expanded our selection products beyond neuroscience research antibodies, these antibodies remains at the core of our business. That's why it's still satisfying to see publications from customers using these antibodies (view them all here), like in three neuroscience publications new this month we'd like to highlight.
In the first publication, Iwate Medical University scientists studied the morphology of P2X3 in rat models utilizing our rabbit anti-P2X3 antibody (cat.# RA10109). Specifically, the investigators explored how P2X3-immunoreactive nerve endings and serosal ganglia interact in the rat gastric antrum.
Image: P2X3 (RA10109) Staining in Rat DRG. Working dilution 1:100 - 1:300.
Read more to learn about the other two publications...
In a second publication, researchers from the University of Basel used our chicken anti-Tyrosine Hydroxylase antibody (cat.# CH23006) to determine the function of the mesencephalic locomotor region (MLR) of the brain. They determined that there are two distinct populations of neurons in the MLR that modulate body movements. Their findings have implications in Parkinson's disease research, along with other areas.
The final publication comes from investigators at the University of Missouri. With the help of our 5HT (serotonin) 2A receptor rabbit antibody (cat.# RA24288), the scientists studied the effects of respiratory motor neuron death in rat models. Their findings help us better understand phrenic long-term facilitation.
- Masato Hirakawa, Takuya Yokoyama, Yoshio Yamamoto, and Tomoyuki Saino. (2021). Morphology of P2X3-Immunoreactive Basket-Like Afferent Nerve Endings Surrounding Serosal Ganglia and Close Relationship with Vesicular Nucleotide Transporter-Immunoreactive Nerve Fibers in the Rat Gastric Antrum. Journal of Comparative Neurology . doi: 10.1002/cne.25219
- Manuel J. Ferreira-Pinto, Harsh Kanodia, Antonio Falasconi, Markus Sigrist, Maria S. Esposito, and Silvia Arber. (2021). Functional Diversity for Body Actions in the Mesencephalic Locomotor Region. Cell . doi: 10.1016/j.cell.2021.07.002
- Lauren F. Borkowski, Catherine L. Smith, Amy N. Keilholz, and Nicole L. Nichols. (2021). Divergent Receptor Utilization is Necessary for Phrenic Long-Term Facilitation Over the Course of Motor Neuron Loss Following CTB-SAP Intrapleural Injections. Journal of Neurophysiology . doi: 10.1152/jn.00236.2021