The latest news from Neuromics, customers, collaborators, and friends. Here we will post publications, data, new reagents, and methods.
For additional information on Neuroscience updates check out our Neuroscience Blog.
Human Brain Cells
When researchers are considering using our human brain cells, they often voice concerns about growth. In order to address these concerns, we explain that we have optimized our media and coatings in order to meet their assay needs.
To the right, we have an example of how our human brain pericytes grow over time. Clearly, growth will not be a concern.
New 3-D Eye Model
We see our world in 3-D. Diseases of the eye compromise this ability.
Neuromics' is pleased to announce that we have a 3-D model aimed at accelerating drug discovery for these diseases. Sight is a terrible thing to lose and the faster new drugs can be discovered, fewer people will have to suffer the loss of sight.
Easy Immunostaining Staining
Time is money. This is especially true of routine immunostaining assays.
Thus, we are pleased to introduce you to EZ-HRP™ Polymer Detection. EZ-HRP™ Polymer Detection's features allow its users to save time, and as a result, money.
Image: Comparison of IHC images using EZ-HRP™ Polymer vs. a conventional avidin-biotin antibody.
New Neuronal Markers
Image: Immunofluorescent analysis of cortical neuron-glial cell culture from E20 rat stained with mouse mAb to GAP43, MO22170, dilution 1:1,000, in red, and costained with chicken pAb to MAP2, dilution 1:10,000, in green. The blue is DAPI staining of nuclear DNA. GAP43 antibody labels protein expressed in the axonal membrane of the neuronal cells, while the MAP2 antibody stains dendrites and perikarya of neurons.
Check out our new antibodies...
ATP and Pain
In dorsal root ganglion (DRG) neurons, ATP is an important neurotransmitter in nociceptive signaling through P2 receptors (P2Rs) such as P2X2/3R, and adenosine is also involved in anti-nociceptive signaling through adenosine A1R.
Check out this publications using our P2X2 Receptor (GP14106) Antibody, where ENNPs interact with P2XRs to metabolize ATP to AMP in DRGs.
Image: Rat DRG stained with Neuromics P2X2R and ENPP1.