Publications using Neuromics' Transfection Kits

i-Fect
Catalog Numbers: NI35150, NI351750
1. Taylor Ludman and Ohannes K Melemedjian. (2019). Bortezomib and metformin opposingly regulate the expression of hypoxia-inducible factor alpha and the consequent development of chemotherapy-induced painful peripheral neuropathy. Molecular Pain. doi: 10.1177/1744806919850043
2. Taylor Ludman and Ohannes K. Melemedjian. (2019). Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy. Molecular Pain. https://doi.org/10.1177/1744806919837429
3. Christopher R. Donnelly. (2018) Neurotrophic Factor Signaling Mechanisms Underlying the Development of Peripheral Neural Circuits (Doctoral Dissertation) University of Michigan
4. Tanaka, Takashi; Shimizu, Shoko; Ueno, Masaki; Fujihara, Yoshitaka; Ikawa, Masahito; Miyata, Shingo. MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors. https://doi.org/10.1016/j.ebiom.2018.03.018
5. Hsiaoyun Lin,Rieko Muramatsu,Noriko Maedera,Hiroto Tsunematsu,Machika Hamaguchi,Yoshihisa Koyama,Mariko Kuroda,Kenji Ono,Makoto Sawada,Toshihide Yamashita. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis. doi.org/10.1016/j.ebiom.2017.10.033
6. Ana Lis Moyano, Jeffrey Steplowski, Haibo Wang, Kyung-No Son, Diana I. Rapolti, Jeffrey Marshall, Vince Elackattu, Michael S. Marshall, Amy K. Hebert, Cory Reiter, Viviana Ulloa, Katarzyna C. Pituch, Maria I. Givogri, Q.Richard Lu, Howard L. Lipton, Ernesto R. Bongarzone. (2018). microRNA-219 reduces viral load and pathologic changes in Theiler’s virus-induced demyelinating disease. Molecular Therapy. DOI: http://dx.doi.org/10.1016/j.ymthe.2018.01.008
7. Ying-jun Liu, Xiao-xi Lin, Jian-qiao Fang, and Fang Fang. Involvement of MrgprC in electroacupuncture analgesia for attenuating CFA-induced thermal hyperalgesia by suppressing the TRPV1 pathway. Pre-pub-full text PDF
8. Zhi-Ling Guo, Liang-Wu Fu, Hou-Fen Su, Stephanie C. Tjen-A-Looi, and John C. Longhurst. Role of TRPV1 in acupuncture modulation of reflex excitatory cardiovascular responses. 3 JAN 2018https://doi.org/10.1152/ajpregu.00405.2017
9. Rui Li, Li-guo Wang, Qi Wang, Zhi-hua Li, Ya-li Ma, Qing-Duo Guo. (2017). Silencing of IRF3 alleviates chronic neuropathic pain following chronic constriction injury. Biomedicine & Pharmacotherapy, doi: 10.1016/j.biopha.2017.01.085.
10. M. Leinders, b, N. Üçeyler, R.A. Pritchard, C. Sommer, L.S. Sorkin. (2016). Increased miR-132-3p expression is associated with chronic neuropathic pain. Experimental Neurology, Volume 283, Part A, Pages 276–286, doi: 10.1016/j.expneurol.2016.06.025
11. C.R. Lin, J.K. Cheng,C.H. Wu,K.H. Chen,C.K. Liu. (2016). Epigenetic suppression of potassium-chloride co-transporter 2 expression in inflammatory pain induced by complete Freund's adjuvant (CFA). European Journal of Pain, doi: 10.1002/ejp.925.
12. Melissa T. Manners, Adam Ertel, Yuzhen Tian and Seena K. Ajit. (2016). Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury. Epigenetics & Chromatin, 20169:23. doi: 10.1186/s13072-016-0073-5
13. Xiaobo Yanga, Heling Chua,Yuping Tanga,& Qiang Donga. (2016). The role of connexin43 in hemorrhagic transformation after thrombolysis in vivo and in vitro. Neuroscience. doi:10.1016/j.neuroscience.2016.04.040
14. Figueroa Johnny D., Serrano-Illan Miguel, Licero Jenniffer, Cordero Kathia, Miranda Jorge D., and De Leon Marino. (2016). Fatty Acid Binding Protein 5 Modulates Docosahexaenoic Acid-Induced Recovery in Rats Undergoing Spinal Cord Injury. Journal of Neurotrauma. doi: 10.1089/neu.2015.4186.
15. Yuhao Zhang, Shao-Rui Chen, Geoffroy Laumet, Hong Chen and Hui-Lin Pan. (2016). Nerve Injury Diminishes Opioid Analgesia through Lysine Methyltransferase-Mediated Transcriptional Repression of µ-Opioid Receptors in Primary Sensory Neurons. Journal of Biological Chemistry, doi: 10.1074/jbc.M115.711812.
16. Liuming Jiang, Qun Wu, Tao Yang. (2016). Silencing of Id2 Alleviates Chronic Neuropathic Pain Following Chronic Constriction Injury. Journal of Molecular Neuroscience, pp 1-7. doi: 10.1007/s12031-016-0713-z
17. Geoffroy Laumet, Judit Garriga, Shao-Rui Chen, Yuhao Zhang, De-Pei Li, Trevor M Smith, Yingchun Dong, Jaroslav Jelinek, Matteo Cesaroni, Jean-Pierre Issa & Hui-Lin Pan. (2015). G9a is essential for epigenetic silencing of K⁺channel genes in acute-to-chronic pain transition. Nature Neuroscience, doi:10.1038/nn.4165.
18. Byung Moon Choi, Soo Han Lee, Sang Mee An, Do Yang Park, Gwan Woo Lee, and Gyu-Jeong Noh. (2015). The time-course and RNA interference of TNF-α, IL-6, and IL-1β expression on neuropathic pain induced by L5 spinal nerve transection in rats. Korean J Anesthesiol. 2015 Apr;68(2):159-169. doi: 10.4097/kjae.2015.68.2.159
19. Ziyi Zhoua, Xiaobai Weib, Jun Xiang, Junpeng Gao, Lixin Wang, Jinsong You, Yefeng Cai , Dingfang Caid. (2015). Protection of erythropoietin against ischemic neurovascular unit injuries through the effects of connexin43. Biochemical and Biophysical Research Communications. doi:10.1016/j.bbrc.2015.02.
20. Y. Xiang, T. Liu, H. Yang, F. Gao, H. Xiang, A. Manyande, Y. Tian and X. Tian. (2014). NRG1-ErbB signalling promotes microglia activation contributing to incision-induced mechanical allodynia. European Journal of Pain, doi: 10.1002/ejp.590.
21. Guo Weizao, Liu Huichen, Li Lin, Yang Man and Du Aihua. (2014). Regulation of lovastatin on a key inflammation-related microRNA in myocardial cells. Chinese Medical Journal, 2014;127(16):2977-2981; doi: 10.3760/cma.j.issn.0366-6999.20140780
22. J. H. Winston, Q. Li, S. K. Sarna. (2013). Chronic prenatal stress epigenetically modifies spinal cord BDNF expression to induce sex-specific visceral hypersensitivity in offspring. Article first published online: 4 MAR 2014. Neurogastroenterology & Motility. doi: 10.1111/nmo.12326.
23. 15. Tiphaine Dolique, Alexandre Favereaux, Olivier Roca-Lapirot, Virginie Roques, Claire Léger, Marc Landy, Frédéric Nagy. (2013). Unexpected association of the “inhibitory” Neuroligin 2 with excitatory PSD95 in neuropathic pain, PAIN, doi: 10.1016/j.pain.2013.07.035.
24. Masaki Ueno,Yuki Fujita, Tatsuhide Tanaka, Yuka Nakamura, Junichi Kikuta, Masaru Ishii & Toshihide Yamashita. (2013). Layer V cortical neurons require microglial support for survival during postnatal development. Nature Neuroscience 16, 543–551 (2013) doi: 10.1038/nn.3358.
25. Sachin Moonat, Amul J. Sakharkar, Huaibo Zhang, Lei Tanga, Subhash C. Pandey. (2013). Aberrant Histone Deacetylase2–Mediated Histone Modifications and Synaptic Plasticity in the Amygdala Predisposes to Anxiety and Alcoholism. Biological Psychiatry, doi: 10.1016/j.biopsych.2013.01.012
26. Tsantoulas C, Zhu L, Shaifta Y, Grist J, Ward JP, Raouf R, Michael GJ, McMahon SB. (2012). Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury. J Neurosci, 32(48):17502-13. doi: 10.1523/JNEUROSCI.3561-12.2012.
27. Masaki Ueno, Yasufumi Hayano1, Hiroshi Nakagawa and Toshihide Yamashita. (2012). Intraspinal rewiring of the corticospinal tract requires target-derived brain-derived neurotrophic factor and compensates lost function after brain injury. Brain, doi: 10.1093/brain/aws053.
28. Jing Chen, Xiaolu Zhang, Handojo Kusumo, Lucio G. Costa, c, Marina Guizzettia. (2013). Cholesterol efflux is differentially regulated in neurons and astrocytes: Implications for brain cholesterol homeostasis. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1831 (2), p.263-275, doi: 10.1016/j.bbalip.2012.09.007
29. Sylvie Diochot, Anne Baron, Miguel Salinas, Dominique Douguet, Sabine Scarzello, Anne-Sophie Dabert-Gay, Delphine Debayle, Valérie Friend, Abdelkrim Alloui, Michel Lazdunski, Eric Lingueglia. (2012). Black mamba venom peptides target acid-sensing ion channels to abolish pain. Nature, doi:10.1038/nature11494.
30. Jacobs VL, Liu Y, De Leo JA. (2012). Propentofylline Targets TROY, a Novel Microglial Signaling Pathway. PLoS ONE, 7(5): e37955. doi: 10.1371/journal.pone.0037955.
siRNA-intact
Catalog Numbers: SI35100

1. Shuangxin Liu, Wei Shi, Houqin Xiao, Xinling Liang, Chunyu Deng, Zhiming Ye, Ping Mei, Suxia Wang, Xiaoying Liu, Zhixin Shan, Yongzheng Liang, Bin Zhang, Wenjian Wang, Yanhui Liu, Lixia Xu, Yunfeng Xia, Jianchao Ma, Zhilian Li. (2012). Receptor Activator of NF-kappaB and Podocytes: Towards a Function of a Novel Receptor-Ligand Pair in the Survival Response of Podocyte Injury. PLoS ONE, doi: 10.1371/journal.pone.0041331

2. Lara Kular, Cyril Rivat, Brigitte Lelongt, Claire Calmel, Maryvonne Laurent, Michel Pohl, Patrick Kitabgi, Stephane Melik-Parsadaniantz and Cecile Martinerie. (2012). NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9. Journal of Neuroinflammation 9:36. doi: 10.1186/1742-2094-9-36.

3. C.-H.Yang, H.-W. Huang, K.-H.Chen, Y.-S.Chen, S.-M.Sheen-Chen and C.-R.Lin. (2011). Antinociceptive potentiation and attenuation of tolerance by intrathecal β-arrestin 2 small interfering RNA in rats. Br. J. Anaesth, doi: 10.1093/bja/aer291.

4. Alexandre Favereaux, Olivier Thoumine, Rabia Bouali-Benazzouz, Virginie Roques, Marie-Amélie Papon, Sherine Abdel Salam, Guillaume Drutel, Claire Léger, André Calas, Frédéric Nagy and Marc Landry. (2011). Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain. The EMBO Journal, doi:10.1038/emboj.2011.249.

5. S. Tumati, W.R. Roeskea, T.M. Largent-Milnesa, T.W. Vanderaha, and EV Varga. (2011). Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats. Journal of Neuroscience, doi: 10.1016/j.jneumeth.2011.04.036.

6. Emmanuel Deval, Jacques Noël, Xavier Gasull1, Anne Delaunay, Abdelkrim Alloui, Valérie Friend, Alain Eschalier, Michel Lazdunski, and Eric Lingueglia. (2011). Acid-Sensing Ion Channels in Postoperative Pain. The Journal of Neuroscience, 31(16): 6059-6066; doi: 10.1523/JNEUROSCI.5266-10.2011.

7. Shuang-Quan Yu, Donna H. Wang. (2011). Intrathecal injection of TRPV1 shRNA leads to increases in blood pressure in rats. Acta Physiologica, doi: 10.1111/j.1748-1716.2011.02285.x.

8. Wu Fx, Bian Jj, Miao Xr, Huang Sd, Xu Xw, Gong Dj, Sun Ym, Lu Zj, Yu Wf. (2010). Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain. Int J Med Sci 2010; 7:251-259. doi: 10.7150/ijms.7.251

9. Joseph George, Naren L. Banik and Swapan K. Ray. (2010). Survivin knockdown and concurrent 4-HPR treatment controlled human glioblastoma in vitro and in vivo. Neuro-Oncology, doi: 10.1093/neuonc/noq079.

10. Philippe Sarret, Louis Doré-Savard, Nicolas Beaudet. (2010). Direct Application of siRNA for In Vivo Pain Research. From: RNA Interference: From Biology to Clinical Applications. Methods in Molecular Biology. Volume: 623; 383-395; doi: 10.1007/978-1-60761-588-0_25.

11. Pascal Fossat, Eric Dobremez, Rabia Bouali-Benazzouz, Alexandre Favereaux, Sandrine S. Bertrand, Kalle Kilk, Claire Léger, Jean-René Cazalets, Ülo Langel, Marc Landry, and Frédéric Nagy. (2010). Knockdown of L Calcium Channel Subtypes: Differential Effects in Neuropathic Pain. The Journal of Neuroscience, January 20, 2010, 30(3):1073-1085; doi: 10.1523/JNEUROSCI.3145-09.2010

12. Yan Chen, Cheng Yang, and Zaijie Jim Wang. (2010). Ca2+/Calmodulin-Dependent Protein Kinase II Is Required for the Initiation and Maintenance of Opioid-Induced Hyperalgesia. The Journal of Neuroscience, 30(1):38-46; doi: 10.1523/JNEUROSCI.4346-09.2010.

13. Joseph George, Naren L. Banik, Swapan K. Ray. (2009). Combination of hTERT Knockdown and IFN-γ Treatment Inhibited Angiogenesis and Tumor Progression in Glioblastoma. Clin Cancer Res, 15(23):7186–95, doi: 10.1158/1078-0432.CCR-09-1425

14. Christian Ndong, Amynah Pradhan, Carole Puma, Jean-Pierre Morello, Cyrla Hoffert, Thierry Groblewski, Dajan O’Donnell, Jennifer M.A. Laird. (2009). Role of rat sensory neuron-specific receptor (rSNSR1) in inflammatory pain: Contribution of TRPV1 to SNSR signaling in the pain pathway. PAIN 143, 130–137. doi: 10.1016/j.pain.2009.02.010

15. Suneeta Tumati, Tally Largent Milnes, Henry I. Yamamura, Todd W. Vanderah, William R. Roeskeand Eva V. Varga. (2008). Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia. European Journal of PharmacologyI, doi: 10.1016/j.ejphar.2008.10.033

16. Louis Doré-Savard, Geneviève Roussy, Marc-André, Dansereau, Michael A Collingwood, Kim A Lennox, Scott D Rose, Nicolas Beaudet, Mark A Behlke and Philippe Sarret. (2008). Central Delivery of Dicer-substrate siRNA: A Direct Application for Pain Research . Molecular Therapy, doi: 10.1038/mt.2008.98

17. X.-W. Dong, S. Goregoaker, H. Engler, X. Zhou, L. Mark, J. Crona, R. Terry, J. Hunter and T. Priestley. (2007). Small interfering RNA-mediated selective knockdown of Na _V1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats. Neuroscience, Volume 146, Issue 2, Pages 812-821; doi: 10.1016/j.neuroscience.2007.01.054

18. Luo MC, Zhang DQ, Ma SW, Huang YY, Shuster SJ, Porreca F, Lai J. (2005). An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons. Molecular Pain, 1:29; doi: 10.1186/1744-8069-1-29

19. Priti Kumar, Sang Kyung Lee, Premlata Shankar, N. Manjunath. A Single siRNA Cynthia C. Tsui, Stuart J. Shankland and Brian A. Pierchala. (2006). Glial Cell Line–Derived Neurotrophic Factor and Its Receptor Ret Is a Novel Ligand-Receptor Complex Critical for Survival Response during Podocyte Injury. JASN Express, doi: 10.1681/ASN.2005080835
n-Fect
Catalog Numbers: NF30150, NF30750

1. Amy N. Sussman, Tong Sun, Ronald M. Krofft, and Raghu V. Durvasula. (2009). Accelerates Disease Progression in Experimental Crescentic Glomerulonephritis. Am. J. Pathol, 174: 1827 - 1836; doi: 10.2353/ajpath.2009.080464

2. Hidetaka Sadanari, Junji Tanaka, Zhuan Li, Rie Yamada, Keiko Matsubara and Tsugiya Murayama. (2009). Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines. Virus Research, doi: 10.1016/j.virusres.2009.01.010.

3. King-Ho Cheung, Diana Shineman, Marioly Müller, César Cárdenas, Lijuan Mei1, Jun Yang, Taisuke Tomita, Takeshi Iwatsubo, Virginia M.-Y. Lee, and J. Kevin Foskett. (2008). Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating. Neuron, doi: 10.1016/j.neuron.2008.04.015

4. Griffin SV, Hiromura K, Pippin J, Petermann AT, Blonski MJ, Krofft R, Takahashi S, Kulkarni AB, Shankland SJ. (2004). Cyclin-Dependent Kinase 5 Is a Regulator of Podocyte Differentiation, Proliferation, and Morphology. Am J Pathol. 165:1175-1185; doi: 10.1016/S0002-9440(10)63378-0
p-Fect
Catalog Numbers: PF30000, PF30001, PF30002, PF30003, PF30075, PF30150, PF30750

1. Hunnicutt BJ , Chaverra M , George L , Lefcort F. (2012). IKAP/Elp1 Is Required In Vivo for Neurogenesis and Neuronal Survival, but Not for Neural Crest Migration. PLoS ONE 7(2): e32050. doi: 10.1371/journal.pone.0032050.

2. Shih-Kuo Chen, Gladys Y.-P. Ko, and Stuart E. Dryer. (2007). Somatostatin Peptides Produce Multiple Effects on Gating Properties of Native Cone Photoreceptor cGMP-Gated Channels That Depend on Circadian Phase and Previous Illumination. J. Neurosci., 27: 12168 - 12175; doi: 10.1523/JNEUROSCI.3541-07.2007.