There is a well choreographed dance between astrocytes, glia. microglia and neurons in the brain. This dance in is highly compartmentalized among different brain cell types to efficiently support various energy-demanding processes.
Astrocytes play a special role. They regulate synaptic transmission fine tuning metabolism and energy management. Another role is supply metabolites such as lactate, serine, and glutamine to support neuronal activity and supply energy.
Here, Neuroscientists, published in "Nature Communications." uncover the role of an endolysosomal transmembrane protein in mediating catabolic processes in astrocytes. Researchers used Neuromics' Primary Human Brain Astrocytes for this study.
Top Image: Graphical representation of study conclusions.
Autophagic flux may work in tandem with reduced LD catabolism to limit the mobilization of toxic lipid species that cause inflammatory cascades in the brain. The neuron-astrocyte. Better understanding flux could be of value in new research approaches for understanding the roots of Neurodegenerative Diseases
Neuromics has a large selection of human astrocytes, including those used in this study, GFP-expressing options, and iPSC-derived astrocytes. You can explore them below.
Have questions? Interested in a quote? We are ready to help - please contact us.
| Name | Catalog # | Type | Species | Applications | Size | Price |
|---|---|---|---|---|---|---|
| GFP Expressing Human Brain Astrocytes | HMP201 | Primary Cells | Human | Cell Assays | 500,000 Cells - Frozen | $1,294.92 |
| Human Brain Astrocytes (HBA) | HMP202 | Primary Cells | Human | Cell Assays | 500,000+ cells - Frozen | $1,022.76 |
| Human Brain Astrocytes (HBA) | HMP202-T25 | Primary Cells | Human | Cell Assays | 500,000+ cells - T25 flask | $1,035.72 |
| Human iPSC - Astrocytes | IPS001 | Primary Cells | Human | Cell Assays | 500,000 Cells | $2,484.00 |
| Human iPSC - Astrocytes (Parkinson’s Disease) | IPS011 | Primary Cells | Human | Cell Assays | 1,000,000 Cells | $2,205.00 |
| Human iPSC - Astrocytes (PSEN2 mutant, N141I, HET) | IPS012 | Primary Cells | Human | Cell Assays | 1,000,000 Cells | $2,205.00 |