Product Details
Catalog Number: CH23006
Applications: ICC, WB, IHC
Type: Chicken IgY
Dilutions: ICC 1:100-1:200; IHC 1:100-1:200; WB 1:250-1:500
Immunogen: Peptide common to mouse (P24529) and human (P07101) TH
Storage: Store at 4°C in the dark
Shipping: Ambient
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 7054
UniProt: X05290
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$99.00Add to Cart

Human TH (EC 1.14.16.2) is a 58,523 dalton protein (528 amino acids) responsible for the enzymatic conversion of l-tyrosine to l-DOPA (dihydroxyphenylalanine). This enzyme is expressed in all catecholaminergic neurons of the CNS and PNS. In the CNS, TH-positive neurons can be found within the substantia nigra, ventral tegmental area, locus ceruleus, and hypothalamus. In the PNS, TH-positive neurons can be found within the sympathetic chain, pre-vertebral ganglia and the adrenal medulla.

Images
TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors.  doi:10.1089/ten.tea.2009.0155.

TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors. doi:10.1089/ten.tea.2009.0155.

TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors.  doi:10.1089/ten.tea.2009.0155.

TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors. doi:10.1089/ten.tea.2009.0155.

Tissue section through an adult mouse brain showing TH (red staining) in catecholaminergic neurons of the substantia nigra (pars compacta). The green staining is the autofluorescence of green fluorescent protein (GFP) in neurons in this transgenic animal.

Tissue section through an adult mouse brain showing TH (red staining) in catecholaminergic neurons of the substantia nigra (pars compacta). The green staining is the autofluorescence of green fluorescent protein (GFP) in neurons in this transgenic animal.