Product Details
This product is no longer available - Contact david@neuromics.com with any questions Human TH (EC 1.14.16.2) is a 58,523 dalton protein (528 amino acids) responsible for the enzymatic conversion of l-tyrosine to l-DOPA (dihydroxyphenylalanine). This enzyme is expressed in all catecholaminergic neurons of the CNS and PNS. In the CNS, TH-positive neurons can be found within the substantia nigra, ventral tegmental area, locus ceruleus, and hypothalamus. In the PNS, TH-positive neurons can be found within the sympathetic chain, pre-vertebral ganglia and the adrenal medulla. |
- Product ReviewsI recommend this product Product Name: Tyrosine Hydroxylase – (Cat# CH23006) Organization: Karolinska InstitutetLaura Pozzi - Sep 29, 2013 - Rating: 5.0
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- Product Publications
Product Publications
- Manuel J. Ferreira-Pinto, Harsh Kanodia, Antonio Falasconi, Markus Sigrist, Maria S. Esposito, and Silvia Arber. (2021). Functional Diversity for Body Actions in the Mesencephalic Locomotor Region. Cell. doi: 10.1016/j.cell.2021.07.002
- Yu-Wei Chen, Manasmita Das, Esteban A. Oyarzabal, Qing Cheng, Nicholas W. Plummer, Kathleen G. Smith, Grace K. Jones, Daniel Malawsky, Jerrel L. Yakel, Yen-Yu Ian Shih & Patricia Jensen (2018). Genetic identification of a population of noradrenergic neurons implicated in attenuation of stress-related responses. Molecular Psychiatry. DOI https://doi.org/10.1038/s41380-018-0245-8
- Hans-Ulrich Fried, U. Benjamin Kaupp and Frank Müller. (2010). Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice. Cell Tissue Res., 339(3): 463–479. doi: 10.1007/s00441-009-0904-9
- Sujoy K. Dhara, Brian A. Gerwe, Anirban Majumder, Mahesh C. Dodla, Nolan L. Boyd, David W. Machacek, Kowser Hasneen, Steven L. Stice. (2009). Genetic Manipulation of Neural Progenitors Derived from Human Embryonic Stem Cells. Tissue Engineering Part A. doi: 10.1089/ten.tea.2009.0155
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- Related Products
Related Products
Name Catalog # Size DOPA decarboxylase RA25065 100 ul Dopamine beta-Hydroxylase RA24600 100 ul phospho-Tyrosine Hydroxylase (Ser40) RA18026 100 ul Tyrosine Hydroxylase CH22122 100 ul Tyrosine Hydroxylase MO20001 100 ul Tyrosine Hydroxylase MO22186 100 ul Tyrosine Hydroxylase MO22941 100 ul Tyrosine Hydroxylase RA21030 50 ug Tyrosine Hydroxylase RA22135 100 ul Tyrosine Hydroxylase SO25000 100 ul
Images
TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors. doi:10.1089/ten.tea.2009.0155.
TH (tyrosine hydroxylase, an excitatory neuronal marker) staining of STEMEZ(TM) hNP1 Human Neural Progenitors. doi:10.1089/ten.tea.2009.0155.
Tissue section through an adult mouse brain showing TH (red staining) in catecholaminergic neurons of the substantia nigra (pars compacta). The green staining is the autofluorescence of green fluorescent protein (GFP) in neurons in this transgenic animal.
Tissue section through an adult mouse brain showing TH (red staining) in catecholaminergic neurons of the substantia nigra (pars compacta). The green staining is the autofluorescence of green fluorescent protein (GFP) in neurons in this transgenic animal.