Product Details
Catalog Number: MC11013
Type: Modulator
Storage: Room Temperature
Shipping: Ambient
Format B: Powdered
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
10 mg$62.00Add to Cart
50 mg$248.00Add to Cart

JZL-184 has been shown to Inhibit MAG lipase (IC50=8 nM) selectively over FAAH. JZL-184 is cell permeable.



1) Long et al. (2009), Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects; Nat. Chem. Biol., 5 37

2) Pan et al. (2009), Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxyl)methyl)piperidine-1-carboxylate (JZL 184) Enhances retrograde endocannabinoid signaling;  J. Pharmacol. Exp. Ther., 331 591

3) Kinsey et al. (2009), Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain; J. Pharmacol. Exp. Ther., 330 902   


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