Product Details
Catalog Number: MC11021
Type: Modulator
Storage: -20°C
Shipping: Ambient
Format B: Powdered
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
10 mg$25.00Add to Cart
50 mg$85.00Add to Cart

Rufinamide is an anticonvulsant medication with clinical applications (1). It inhibits Nav1.1 and Nav1.6 activation (2). In gerbils, Rufinamide improved cognitive function and increased neurogenesis by increasing IGF-1, IGF-1R, and p-CREB (3).



1) Hakimian et al. (2007), Rufinamide: a new anti-epileptic medication; Expert Opin.Pharmacother. 8 1931

2) Gilchrist et al. (2014), Nav1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents; ACS Chem.Biol. 9 1204

3) Chen et al. (2018), Rufinamide, an antiepileptic drug, improves cognition and increases neurogenesis in the aged gerbil hippocampal dentate gyrus via increasing expressions of IGF-1, IGF-1R and p-CREB; Chem.Biol.Interact 286 71


Product Image Unavailable