Product Details
Catalog Number: PR27076
Type: Protein
Storage: Store at room temperature for up to 3 weeks. Store desiccated at -20°C. Avoid freeze-thaw cycles.
Shipping: Ambient
Format B: lyophilized
Species Reactivity: Human, Mouse
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
10 ug$205.00Add to Cart
2 ug$108.00Add to Cart

Interleukin-3 is a pleiotropic cytokine produced primarily by activated T cells. IL-3 is thought to function via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines. IL-3 has also been shown to affect the functional activity of a variety of other cell types including mast cells, eosinophils, megakaryocytes and basophils.
Interleukin-3 mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 135 amino acids and having a molecular mass of 15100 Dalton.
The IL-3 is purified by proprietary chromatographic techniques.

1. Constitutive activation of JAK2 confers murine interleukin-3-independent survival and proliferation of BA/F3 cells.  J Biol Chem 1999 Mar 5;274(10):6342-9.
2. The diphtheria toxin transmembrane domain as a pH sensitive membrane anchor for human interleukin-2 and murine interleukin-3.  Protein Eng 1998 Nov;11(11):1111-20.
3. Homodimeric murine interleukin-3 agonists indicate that ligand dimerization is important for high-affinity receptor complex formation.  Growth Factors 1994;10(1):17-27.
4. Stem cell responses in myelosuppressed mice following sequential treatment with recombinant human interleukin 1 (rHuIL-1), recombinant murine interleukin 3 (rMuIL-3) and recombinant human macrophage colony-stimulating factor (rHuM-CSF).  Stem Cells 1994 Jan;12(1):103-13.
5. The c-kit receptor transduces the stem cell factor-triggered growth signal in murine interleukin-3-dependent cell line.  Cytotechnology 1994;16(1):27-35.
6. Retroviral-media ted transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.  Exp Hematol 1993 Aug;21(9):1245-54.

IL-3 Mouse Structure and Sequence

IL-3 Mouse Structure and Sequence

We can help.

We are building our company one satisfied customer at a time. If you have any questions or concerns, please contact us.

5325 West 74th St., Suite 8
Edina, MN 55439

Toll free: 866-350-1500
Int’l phone: 952-374-6161
Fax: 612-677-3976