Carcinoma associated fibroblasts (CAFs) have recently been implicated in important aspects of epithelial solid tumor biology such as neoplastic progression, tumor growth, angiogenesis, and metastasis. Human Breast CAFs are isolated from human breast tumor tissue. Cells are grown in T75 tissue culture flasks. Prior to shipping, cells at passage 1 are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1,000,000 cells.
Human Breast Cancer CAFs can be used for the assay of cell-cell interaction, adhesion, PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications. Cells can be expanded for 3-5 passages.
Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.
- Product Reviews
- Product Publications
- Sunil Singh. (2021). Engineered Organotypic Breast Tumor Model for Mechanistic Studies of Tumor-Stromal Interactions and Drug Discovery. University of Akron, Doctoral Dissertation
- Luis P. Ferreira, Vitor M. Gaspar, Maria V. Monteiro, Bruno Freitas, Nuno J.O. Silva, and Joao F. Mano. (2020). Screening of Dual Chemo-Photothermal Cellular Nanotherapies in Organotypic Breast Cancer 3D Spheroids. Journal of Controlled Release. doi: 10.1016/j.jconrel.2020.12.054
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