Product Details
Catalog Number: CH22102
Applications: ICC, WB, IHC
Type: Chicken IgY
Dilutions: ICC 1:2000; IHC 1:2000; WB 1:10,000
Immunogen: Purified bovine spinal cord GFAP
Storage: Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles
Format A: liquid
Species Reactivity: Human, Mouse, Rat, Primate
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$275.00Add to Cart

Glial fibrillary acidic protein (GFAP) is the 10nm or intermediate filament protein found specifically in astrocytic cells in the central nervous system.

GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells.

Images
GFAP (red) staining of astrocytes in primary culture (DAPI, blue).

GFAP (red) staining of astrocytes in primary culture (DAPI, blue).

GFAP (red) staining of astrocytes in primary culture (DAPI, blue).

GFAP (red) staining of astrocytes in primary culture (DAPI, blue).

Western blot of whole rat cerebellum homogenate stained with GFAP, at dilution of 1:100,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~50kDa corresponds to rodent GFAP. A lower band at ~45kDa is derived from the GFAP molecule.

Western blot of whole rat cerebellum homogenate stained with GFAP, at dilution of 1:100,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~50kDa corresponds to rodent GFAP. A lower band at ~45kDa is derived from the GFAP molecule.

Western blot of whole rat cerebellum homogenate stained with GFAP, at dilution of 1:100,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~50kDa corresponds to rodent GFAP. A lower band at ~45kDa is derived from the GFAP molecule.

Western blot of whole rat cerebellum homogenate stained with GFAP, at dilution of 1:100,000. A prominent band running with an apparent SDS-PAGE molecular weight of ~50kDa corresponds to rodent GFAP. A lower band at ~45kDa is derived from the GFAP molecule.