Immunohistochemical staining for Vimentin is also characteristic of sarcomas (of neural, muscle and fibroblast origin) compared to carcinomas which are generally negative. Melanomas, lymphomas and vascular tumors may all stain for Vimentin. Vimentin antibodies are thus of value in the differential diagnosis of undifferentiated neoplasms and malignant tumors.
Vimentin protein is found in the eye lens and cornea, and found in mesenchymal tissues in adult mammals. In the CNS, it is found in endothelia cells and developing neurons, developing and some mature astrocytes, microglia, mature Bergmann glia and ependymal. Vimentin antibodies are useful in studying stem cells.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size ALDH1L1 RA22119 100 ul Coronin 1a/p57 RA22108 100 ul GAP43 RA22115 100 ul GFAP CH22102 100 ul GFAP CH23011 200 ul GFAP RA22101 100 ul Glial Fibrillary Acidic Protein (GFAP) MO22101 100 ul IBA1 Polyclonal Rabbit Antibody RA22133 100 ul SOX-2/SRY (sex determining region Y)-box 2 MO47038 100 ul SRY (Sex Determining Region Y)-Box 11/SOX-11 MO47052 100 ul Vimentin CH22108 100 ul Vimentin MO22115 100 ul Vimentin RA22124 100 ul of Serum