Human brain microvascular pericytes have many functions including a critical role in the formation and function of the blood-brain barrier, regulation of angiogenses, survival of endothelial cells and phagocytosis of cellular debris.
Human Brain Microvascular Perictyes were isolated from normal human brain cortical tissue. Puromycin resistance HBMVPCs are shipped at passage 3 on dry ice in a vial. Pericyte-Growth medium containing 5% fetal bovine serum and growth supplement (PGB001) is recommended for culture. Cells have an average additional population doubling levels >12 when cultured.
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- Ece Bayir, M. Mert Celtikoglu, Aylin Sendemir. (2018). The use of bacterial cellulose as a basement membrane improves the plausibility of the static in vitro blood-brain barrier model. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2018.12.257
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