Product Details
Catalog Number: MO15013
Applications: ICC, WB, IHC, IF
Type: Mouse IgG
Immunogen: Microtubules derived from rat brain
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Entrez: 10381
UniProt: Q13509
Downloads: Datasheet (pdf)
Product Sizes
| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ug | $305.00 | Add to Cart |
Human β-Tubulin 3 is a 50,432 dalton structural protein (450 amino acid) expressed in neurons of the PNS and CNS. It contributes to microtubule stability in neuronal cell bodies and axons, and plays a role in axonal transport. |
- Product ReviewsExcellent product, quick shipping! Product Name: Tuj1, Mouse – (Cat# MO15013) https://www.neuromics.com/MO15013 Organization: University of StanfordAlexa - Jan 31, 2018 - Rating: 5.0First order from neuromics and everything went without any issue. Product Name: Tuj 1, Mouse – (Cat# MO15013) http://bit.ly/1Qx4ASc Organization: Stanford UniversityTian TianW - May 01, 2016 - Rating: 5.0Staining (Tuj1) worked well on human neural progenitor cells. Product Name: Tuj 1, Mouse – (Cat# MO15013-100) http://bit.ly/1Qx4ASc Organization: UCONNStephen Crocker - Nov 19, 2015 - Rating: 5.0
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- Product Publications
Product Publications
- Haibing Yue, Kai Xie, Xianglin Ji, Bingzhe Xu, Chong Wang, and Peng Shi. (2020). Vascularized Neural Constructs for Ex-Vivo Reconstitution of Blood-Brain Barrier Function.Biomaterials. doi: 10.1016/j.biomaterials.2020.119980
- Patrick Luningschror, Georg Werner, Stijn Stroobants, Soichiro Kakuta, Benjamin Dombert, Daniela Sinske, Renate Wanner, Renate Lullmann-Rauch, Benedikt Wefers, Wolfgang Wurst, Rudi D’Hooge, Yasuo Uchiyama, Michael Sendtner, Christian Haass, Paul Saftig, Bernd Knoll, Anja Capell, and Markus Damme. (2020). The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.Cell Reports, 30(10), 3506-3519. doi: 10.1016/j.celrep.2020.02.060
- Shasha Zhang,Yuan Zhang,Ying Dong, Lingna Guo, Zhong Zhang, Buwei Shao, Jieyu Qi, Han Zhou, Weijie Zhu, Xiaoqian Yan, Guodong Hong, Liyan Zhang, Xiaoli Zhang, Mingliang Tang, Chunjie Zhao, Xia Gao, Renjie Chai. (2019). Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-019-03291-2
- B. Vindondo, S. Stettler, A. Stojiljkovic, H. Mogel, V. Gaschen, C. Spadavecchia, D. Casoni, M.H. Stoffel. (2019). Assessment of Potential Neuropathic Changes in Cattle After Cautery Disbudding. Research in Veterinary Science. doi: 10.1016/j.rvsc.2019.08.003
- Zahra N. Sayyid, Tian Wang, Leon Chen, Sherri M. Jones, Alan G. Cheng. (2019). Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System. Cell Reports, Vol. 28, Issue 2, pg. 312-324. doi: 10.1016/j.celrep.2019.06.028
- Zuzana Krejciova, George A. Carlson, Kurt Giles and Stanley B. Prusiner (2019). Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein. Acta Neuropathologica Communications 20197:81 https://doi.org/10.1186/s40478-019-0703-9Arantxa Bolinches-Amorós, Marian León, Verónica del Buey Furió, Gemma Marfany, Roser Gonzàlez-Duarte, Slaven Erceg, Dunja Lukovic (2019). Generation of an iPSC line from a retinitis pigmentosa patient carrying a homozygous mutation in CERKL and a healthy sibling. Stem Cell Research. https://doi.org/10.1016/j.scr.2019.101455
- Cristina Martínez‐Ramos, Laura Rodríguez Doblado, Eric López Mocholi, Ana Alastrue‐Agudo, Marina Sánchez Petidier, Esther Giraldo, Manuel Monleón Pradas, Victoria Moreno‐Manzano (2019). Biohybrids for spinal cord injury repair. Journal of Tissue Engineering and Regenerative Medicine. https://doi.org/10.1002/term.2816
- Ana Artero Castro, Kathleen Long, Andrew Bassett, Candela Machuca Arellano, Marian León, Almudena Ávila-Fernandeze , Marta Cortón, Toni Vidal-Puig, Carmen Ayuso, Dunja Lukovic, Slaven Erceg. (2018). Generation of gene-corrected human induced pluripotent stem cell lines derived from retinitis pigmentosa patient with Ser331Cysfs*5 mutation in MERTK. Stem Cell Research. https://doi.org/10.1016/j.scr.2018.11.003
- Patrick Lüningschrör, Beyenech Binotti, Benjamin Dombert, Peter Heimann, Angel Perez-Lara, Carsten Slotta, Nadine Thau-Habermann, Cora R. von Collenberg, Franziska Karl, Markus Damme, Arie Horowitz, Isabelle Maystadt8, Annette Füchtbauer, Ernst-Martin Füchtbauer, Sibylle Jablonka, Robert Blum, Nurcan Üçeyler, Susanne Petri, Barbara Kaltschmidt, Reinhard Jahn, Christian Kaltschmidt2 & Michael Sendtner. (2018). Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nature Communications. DOI: 10.1038/s41467-017-00689-z
- C. Machuca Arellano, A. Vilches, E. Clemente, S.I. Pascual-Pascual, A. Bolinches-Amoros, A. Artera Castro, C. Espinos, M.L. Rodriguez, P. Jendelova, S. Erceg. (2018). Generation of a Human iPSC Line From a Patient With Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) Caused By Mutation in SACSIN Gene. Stem Cell Research. Doi: 10/1016/j.scr.2018.07.012
- Qianqian Yang, Gaoying Sun, Haiyan Yin, Hongrui Li, hixin Cao, Jinghan Wang, Jeijuan Zhou, Haibo Wang, Jianfeng Li. (2018) PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway. Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2018.02.025
- Jackelien van Scheppingen, James D. Mills, Till S. Zimmer, Diede W.M. Broekaart, Valentina Iori, Anika Bongaarts, Jasper J. Anink, Anand M. Iyer, Anatoly Korotkov, Floor E. Jansen, Wim van Hecke, Wim G. Spliet, Peter C. van Rijen,
Johannes C. Baayen, Annamaria Vezzani, Erwin A. van Vliet, Eleonora Aronica. (2018). miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes. Glia. 2018;00:1–16. https://doi.org/10.1002/glia.23302 - Jintao Du, Xianren Wang, Xiaobo Zhang, Xuemei Zhang, and Hongyan Jiang. DNER modulates the length, polarity and synaptogenesis of spiral ganglion neurons via the Notch signaling pathway. Molecular Medicine Reports. DOI: 10.3892/mmr.2017.8115
- Ola Awad, Leelamma M. Panicker, Rania M. Deranieh, Manasa P. Srikanth, Robert A. Brown, Antanina Voit, Tejasvi Peesay, Tea Soon Park, Elias T. Zambidis, and Ricardo A. Feldman. (2017). Altered Differentiation Potential of Gaucher’s Disease iPSC Neuronal Progenitors due to Wnt/b-Catenin Downregulation. Stem Cell Reports doi: 10.1016/j.stemcr.2017.10.029
- D. Soscia, A. Belle, N. Fischer, H. Enright, A. Sales, J. Osburn, W. Benett, E. Mukerjee, K. Kulp, S. Pannu, and E. Wheeler. (2017). Controlled placement of multiple CNS cell populations to create complex neuronal cultures. PLoS ONE 12 (11): 0188146. https://doi.org/10.1371/journal.pone.0188146
- Patrick Lüningschrör, Beyenech Binotti, Benjamin Dombert, Peter Heimann, Angel Perez-Lara, Carsten Slotta, Nadine Thau-Habermann, Cora R. von Collenberg, Franziska Karl, Markus Damme, Arie Horowitz, Isabelle Maystadt, Annette Füchtbauer, Ernst-Martin Füchtbauer, Sibylle Jablonka, Robert Blum, Nurcan Üçeyler, Susanne Petri, Barbara Kaltschmidt, Reinhard Jahn, Christian Kaltschmidt & Michael Sendtner. (2017) Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nature Communications. doi:10.1038/s41467-017-00689-z
- Jintao Du Xuemei Zhang, Hui Cao, Di Jiang, Xianren Wang, Wei Zhou, Kaitian Chen, Jiao Zhou, Hongyan Jiang, Luo Ba. (2017). MiR-194 is involved in morphogenesis of spiral ganglion neurons in inner ear by rearranging actin cytoskeleton via targeting RhoB. International Journal of Developmental Neuroscience. doi: 10.1016/j.ijdevneu.2017.09.004
- Di Jiang, Jintao Du, Xuemei Zhang, Wei Zhou, Lin Zong, Chang Dong, Kaitian Chen, Yu Chen, Xihui Chen, and Hongyan Jiang. (2016). miR-124 promotes the neuronal differentiation of mouse inner ear neural stem cells. International Journal of Molecular Medicine, Volume 38 Issue 5. doi: 10.3892/ijmm.2016.2751
- Thomas V. Johnson; Ericka N. Oglesby; Matthew R. Steinhart; Elizabeth Cone-Kimball; Joan Jefferys; Harry A. Quigley. (2016). Time-Lapse Retinal Ganglion Cell Dendritic Field Degeneration Imaged in Organotypic Retinal Explant Culture. Investigative Ophthalmology & Visual Science, Vol.57, 253-264. doi: 10.1167/iovs.15-17769
- Loïc Binan, Charlène Tendey, Gregory De Crescenzo, Rouwayda El Ayoubi, Abdellah Ajji, Mario Jolicoeur. (2013). Differentiation of neuronal stem cells into motor neurons using electrospun poly-l-lactic acid/gelatin scaffold Biomaterials. Biomaterials, doi: 10.1016/j.biomaterials.2013.09.097
- Dirk Puehringer, Nadiya Orel, Patrick Lüningschrör, Narayan Subramanian, Thomas Herrmann, Moses V Chao & Michael Sendtner. (2013). EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons. Nature Neuroscience 16, 407–415 (2013) doi: 10.1038/nn.3333
- Leanne M. Ramer, A. Peter van Stolk, Jessica A. Inskip, Matt S. Ramer and Andrei V. Krassioukov. (2012). Plasticity of TRPV1-expressing sensory neurons mediating autonomic dysreflexia following spinal cord injury. Front. Physiol., doi: 10.3389/fphys.2012.00257
- A. Young, D.W. Machacek, S.K. Dhara, P.R. MacLeish, M. Benveniste, M.C. Dodla, C.D. Sturkie and S.L. Stice. (2011). Ion channels and ionotrophic receptors in a human embryonic stem cell derived neural progenitors. Neuroscience, doi: 10.1016/j.neuroscience.2011.04.039
- C. Bettina Portmann-Lanz PhD, Andreina Schoeberlein PhD, Reto Portmann PhD, Stefan Mohr MD, Pierre Rollini PhD, Ruth Sager and Daniel V. Surbek MD. (2010). Turning placenta into brain: placental mesenchymal stem cells differentiate into neurons and oligodendrocytes. American Journal of Obstetrics and Gynecology, doi: 10.1016/j.ajog.2009.10.893
- Alonso M. Higuero, Lucía Sánchez-Ruiloba, Laura E. Doglio, Francisco Portillo, José Abad- Rodríguez, Carlos G. Dotti and Teresa Iglesias. (2009). Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development. Journal of Biological Chemistry, doi: 10.1074/jbc.M109.024703
- Vidya Murthy, Stéphane F. Maison, Julián Taranda, Nadeem Haque, Chris T. Bond, A. Belén Elgoyhen, John P. Adelman, M. Charles Liberman, Douglas E. Vetter. (2009). SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells. Molecular and Cellular Neuroscience, 40, 39–49. doi: 10.1016/j.mcn.2008.08.011
- Sujoy K. Dhara, Kowser Hasneen, David W. Machacek, Nolan L. Boyd, Raj R. Rao, Steven L. Stice. (2008). Human neural progenitor cells derived from embryonic stem cells in feeder-free cultures. Differentiation, 76 (5), 454–464. doi: 10.1111/j.1432-0436.2007.00256.x
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Images
Tuj-1 staining of Neuron-specific class III β-tubulin in differentiated human neural progenitor cells. Cells were stained using goat anti-mouse Alexa Fluor 488 (green) secondary antibody (Molecular Probe, A-11001) and counterstained with PI (red).
Tuj-1 staining of Neuron-specific class III β-tubulin in differentiated human neural progenitor cells. Cells were stained using goat anti-mouse Alexa Fluor 488 (green) secondary antibody (Molecular Probe, A-11001) and counterstained with PI (red).
Neural progenitors were labeled with anti-rat Nestin polyclonal antibody (Cat#:GT15114) and stained with conjugated donkey anti-goat secondary anti-body (green). Differentiated neurons were labeled with neuron-specific mouse anti-β-III tubulin/ Tuj1-(Cat#MO15013 monoclonal antibody (red). Nuclei were stained with DAPI (blue)
Neural progenitors were labeled with anti-rat Nestin polyclonal antibody (Cat#:GT15114) and stained with conjugated donkey anti-goat secondary anti-body (green). Differentiated neurons were labeled with neuron-specific mouse anti-β-III tubulin/ Tuj1-(Cat#MO15013 monoclonal antibody (red). Nuclei were stained with DAPI (blue)
Immunostaining of hNP1 Progenitors before and after differentiation. The culture was highly homogenous with neural rosettes. Differentiation (2007) DOI: 10.1111/j.1432-0436.2007.00256.x...Dilutions: NES (1:100, Neuromics, Edina, MN), MSI1 (1:100, Neuromics), Tuj1 (1:500, Neuromics)...
Immunostaining of hNP1 Progenitors before and after differentiation. The culture was highly homogenous with neural rosettes. Differentiation (2007) DOI: 10.1111/j.1432-0436.2007.00256.x...Dilutions: NES (1:100, Neuromics, Edina, MN), MSI1 (1:100, Neuromics), Tuj1 (1:500, Neuromics)...