Product Details
Catalog Number: MO15013
Applications: ICC, WB, IHC, IF
Type: Mouse IgG
Immunogen: Microtubules derived from rat brain
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Entrez: 10381
UniProt: Q13509
Downloads: Datasheet (pdf)
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Human β-Tubulin 3 is a 50,432 dalton structural protein (450 amino acid) expressed in neurons of the PNS and CNS. It contributes to microtubule stability in neuronal cell bodies and axons, and plays a role in axonal transport. Product Highlights: |
- Product ReviewsExcellent product, quick shipping! Product Name: Tuj1, Mouse – (Cat# MO15013) https://www.neuromics.com/MO15013 Organization: University of StanfordAlexa - Jan 31, 2018 - Rating: 5.0First order from neuromics and everything went without any issue. Product Name: Tuj 1, Mouse – (Cat# MO15013) http://bit.ly/1Qx4ASc Organization: Stanford UniversityTian TianW - May 01, 2016 - Rating: 5.0Staining (Tuj1) worked well on human neural progenitor cells. Product Name: Tuj 1, Mouse – (Cat# MO15013-100) http://bit.ly/1Qx4ASc Organization: UCONNStephen Crocker - Nov 19, 2015 - Rating: 5.0
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- Product Publications
Product Publications
- Marina Sanchez-Petidier, Consuelo Guerri, and Victoria Moreno-Manzano. (2021). Toll-Like Receptors 2 and 4 Differentially Regulate the Self-Renewal and Differentiation of Spinal Cord Neural Precursor Cells. doi: 10.21203/rs.3.rs-532850/v1
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- E. Fowler, J. Rosen, S.M. Shah, L. Strowd, J.C. Tang, L.A. Nattkemper, and G. Yosipovitch. (2020). Immunohistochemistry Analysis of Itch and Pain Mediators in Nonmelanoma Skin Cancer. Journal of the European Academy of Dermatology and Venereology. doi: 10.1111/jdv.16717
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- B. Vindondo, S. Stettler, A. Stojiljkovic, H. Mogel, V. Gaschen, C. Spadavecchia, D. Casoni, M.H. Stoffel. (2019). Assessment of Potential Neuropathic Changes in Cattle After Cautery Disbudding. Research in Veterinary Science. doi: 10.1016/j.rvsc.2019.08.003
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- C. Machuca Arellano, A. Vilches, E. Clemente, S.I. Pascual-Pascual, A. Bolinches-Amoros, A. Artera Castro, C. Espinos, M.L. Rodriguez, P. Jendelova, S. Erceg. (2018). Generation of a Human iPSC Line From a Patient With Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) Caused By Mutation in SACSIN Gene. Stem Cell Research. Doi: 10/1016/j.scr.2018.07.012
- Qianqian Yang, Gaoying Sun, Haiyan Yin, Hongrui Li, hixin Cao, Jinghan Wang, Jeijuan Zhou, Haibo Wang, Jianfeng Li. (2018) PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway. Free Radical Biology and Medicine. https://doi.org/10.1016/j.freeradbiomed.2018.02.025
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Johannes C. Baayen, Annamaria Vezzani, Erwin A. van Vliet, Eleonora Aronica. (2018). miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes. Glia. 2018;00:1–16. https://doi.org/10.1002/glia.23302 - Jintao Du, Xianren Wang, Xiaobo Zhang, Xuemei Zhang, and Hongyan Jiang. DNER modulates the length, polarity and synaptogenesis of spiral ganglion neurons via the Notch signaling pathway. Molecular Medicine Reports. DOI: 10.3892/mmr.2017.8115
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- D. Soscia, A. Belle, N. Fischer, H. Enright, A. Sales, J. Osburn, W. Benett, E. Mukerjee, K. Kulp, S. Pannu, and E. Wheeler. (2017). Controlled placement of multiple CNS cell populations to create complex neuronal cultures. PLoS ONE 12 (11): 0188146. https://doi.org/10.1371/journal.pone.0188146
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- Jintao Du Xuemei Zhang, Hui Cao, Di Jiang, Xianren Wang, Wei Zhou, Kaitian Chen, Jiao Zhou, Hongyan Jiang, Luo Ba. (2017). MiR-194 is involved in morphogenesis of spiral ganglion neurons in inner ear by rearranging actin cytoskeleton via targeting RhoB. International Journal of Developmental Neuroscience. doi: 10.1016/j.ijdevneu.2017.09.004
- Di Jiang, Jintao Du, Xuemei Zhang, Wei Zhou, Lin Zong, Chang Dong, Kaitian Chen, Yu Chen, Xihui Chen, and Hongyan Jiang. (2016). miR-124 promotes the neuronal differentiation of mouse inner ear neural stem cells. International Journal of Molecular Medicine, Volume 38 Issue 5. doi: 10.3892/ijmm.2016.2751
- Thomas V. Johnson; Ericka N. Oglesby; Matthew R. Steinhart; Elizabeth Cone-Kimball; Joan Jefferys; Harry A. Quigley. (2016). Time-Lapse Retinal Ganglion Cell Dendritic Field Degeneration Imaged in Organotypic Retinal Explant Culture. Investigative Ophthalmology & Visual Science, Vol.57, 253-264. doi: 10.1167/iovs.15-17769
- Loïc Binan, Charlène Tendey, Gregory De Crescenzo, Rouwayda El Ayoubi, Abdellah Ajji, Mario Jolicoeur. (2013). Differentiation of neuronal stem cells into motor neurons using electrospun poly-l-lactic acid/gelatin scaffold Biomaterials. Biomaterials, doi: 10.1016/j.biomaterials.2013.09.097
- Dirk Puehringer, Nadiya Orel, Patrick Lüningschrör, Narayan Subramanian, Thomas Herrmann, Moses V Chao & Michael Sendtner. (2013). EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons. Nature Neuroscience 16, 407–415 (2013) doi: 10.1038/nn.3333
- Leanne M. Ramer, A. Peter van Stolk, Jessica A. Inskip, Matt S. Ramer and Andrei V. Krassioukov. (2012). Plasticity of TRPV1-expressing sensory neurons mediating autonomic dysreflexia following spinal cord injury. Front. Physiol., doi: 10.3389/fphys.2012.00257
- A. Young, D.W. Machacek, S.K. Dhara, P.R. MacLeish, M. Benveniste, M.C. Dodla, C.D. Sturkie and S.L. Stice. (2011). Ion channels and ionotrophic receptors in a human embryonic stem cell derived neural progenitors. Neuroscience, doi: 10.1016/j.neuroscience.2011.04.039
- C. Bettina Portmann-Lanz PhD, Andreina Schoeberlein PhD, Reto Portmann PhD, Stefan Mohr MD, Pierre Rollini PhD, Ruth Sager and Daniel V. Surbek MD. (2010). Turning placenta into brain: placental mesenchymal stem cells differentiate into neurons and oligodendrocytes. American Journal of Obstetrics and Gynecology, doi: 10.1016/j.ajog.2009.10.893
- Alonso M. Higuero, Lucía Sánchez-Ruiloba, Laura E. Doglio, Francisco Portillo, José Abad- Rodríguez, Carlos G. Dotti and Teresa Iglesias. (2009). Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development. Journal of Biological Chemistry, doi: 10.1074/jbc.M109.024703
- Vidya Murthy, Stéphane F. Maison, Julián Taranda, Nadeem Haque, Chris T. Bond, A. Belén Elgoyhen, John P. Adelman, M. Charles Liberman, Douglas E. Vetter. (2009). SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells. Molecular and Cellular Neuroscience, 40, 39–49. doi: 10.1016/j.mcn.2008.08.011
- Sujoy K. Dhara, Kowser Hasneen, David W. Machacek, Nolan L. Boyd, Raj R. Rao, Steven L. Stice. (2008). Human neural progenitor cells derived from embryonic stem cells in feeder-free cultures. Differentiation, 76 (5), 454–464. doi: 10.1111/j.1432-0436.2007.00256.x
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Images
Tuj-1 staining of Neuron-specific class III β-tubulin in differentiated human neural progenitor cells. Cells were stained using goat anti-mouse Alexa Fluor 488 (green) secondary antibody (Molecular Probe, A-11001) and counterstained with PI (red).
Tuj-1 staining of Neuron-specific class III β-tubulin in differentiated human neural progenitor cells. Cells were stained using goat anti-mouse Alexa Fluor 488 (green) secondary antibody (Molecular Probe, A-11001) and counterstained with PI (red).
Neural progenitors were labeled with anti-rat Nestin polyclonal antibody (Cat#:GT15114) and stained with conjugated donkey anti-goat secondary anti-body (green). Differentiated neurons were labeled with neuron-specific mouse anti-β-III tubulin/ Tuj1-(Cat#MO15013 monoclonal antibody (red). Nuclei were stained with DAPI (blue)
Neural progenitors were labeled with anti-rat Nestin polyclonal antibody (Cat#:GT15114) and stained with conjugated donkey anti-goat secondary anti-body (green). Differentiated neurons were labeled with neuron-specific mouse anti-β-III tubulin/ Tuj1-(Cat#MO15013 monoclonal antibody (red). Nuclei were stained with DAPI (blue)
Immunostaining of hNP1 Progenitors before and after differentiation. The culture was highly homogenous with neural rosettes. Differentiation (2007) DOI: 10.1111/j.1432-0436.2007.00256.x...Dilutions: NES (1:100, Neuromics, Edina, MN), MSI1 (1:100, Neuromics), Tuj1 (1:500, Neuromics)...
Immunostaining of hNP1 Progenitors before and after differentiation. The culture was highly homogenous with neural rosettes. Differentiation (2007) DOI: 10.1111/j.1432-0436.2007.00256.x...Dilutions: NES (1:100, Neuromics, Edina, MN), MSI1 (1:100, Neuromics), Tuj1 (1:500, Neuromics)...