Proliferating Cell Nuclear Antigen, PCNA or Cyclin Antibody

Product Details

Catalog Number: MO20014

Applications: WB, IHC, FC

Type: Mouse IgG

Immunogen: Clone: PC10. Rat PCNA induced in the protein A expression vector pR1T2T (Wassem and Lane, 1990).

Storage: Store at 4°C short term. Store at -20°C long term. Avoid freeze-thaw cycles.

Shipping: Frozen (Polar Packs)

Format A: Protein G Purified

Format B: liquid

Species Reactivity: Human, Mouse, Rat, Primate

Entrez: 5111

UniProt: P12004

RRID: AB_2160349

Downloads: SDS (pdf)

Downloads: Datasheet (pdf)

Product Sizes

Size	List Price	Price	Cart
100 ul		$155.00	Add to Cart

Proliferating cell nuclear antigen (PCNA) is a 36kD protein which is highly conserved between species. PCNA functions as a co-factor for DNA polymerase delta in S phase and also during DNA synthesis associated with DNA damage repair mechanisms. The PCNA molecule has a half-life in excess of 20 hours, and therefore, may be detected in non-cycling cells eg those in G0 phase.

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Product Publications

Wei Han, Gui-Nan Liu. (2009). EGR-1 decoy ODNs inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia of balloon-injured arteries in rat. Life Sciences, doi: 10.1016/j.lfs.2009.12.005

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Images

PCNA staining of Human seminoma: Note nuclear staining of proliferating tumor cells. Paraffin section.