Calretinin (CAL6). a member of the family of so-called EF-hand proteins that also includes S-100 proteins, is a 29 kDa calcium binding protein that is expressed in central and peripheral nervous system and in many normal and pathological tissues.
Outside the nervous system, calretinin is reported to be expressed in a range of cell types including mesothelial cells, steroid producing cell, (eg adrenal cortical cells, Leydig cells, ovarian theca interna cells as well as Sertoli cells, some neuroendocrine cells, eccrine sweat glands) and other cell types.
The presence of calretinin is reported to be a useful marker primarily for differentiating malignant mesothelioma from carcinomas. Other reports indicate the detection of calretinin is helpful for the differential characterization of ovarian stroma tumors. Calretinin-positive cells have also been reported in the convoluted tubules of the kidney with some antibodies.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Bradykinin Receptor B2 RA14137 100 ul CADM1/SynCAM RA25084 100 ul Calbindin CH22118 100 ul Calbindin MO20016 100 ug Calbindin D MO15097 100 ug Calcineurin A MO15055 100 ug Calreticulin MO22164 100 ul Calretinin CH22116 100 ul Calretinin MO22166 100 ul Calretinin (IgG1) MO22165 100 ul CaMKII RA18006 100 ul CaMKII2A GT41019 100 ug Cav1.2 Ca2+ channel MO50006 100 ul Cav1.3 Ca2+ channel MO50007 100 ul Cav3.1 Ca2+ channel MO50008 100 ul MARCKS (Myristoylated Alanine Rich C Kinase Substrate) RA22111 100 ul Neurogranin precursor GT41024 100 ug phospho-Synapsin (Ser9) RA18009 100 ul S100B GT15160 100 ug SHANK1a C-terminus RA19016 100 ug SHANK1a N-Terminus RA19015 100 ug Striatin RA25067 100 ul Synapsin RA18010 100 ul Synaptotagmin 1 MO15099 100 ug VAMP-1 GT15236 100 ug