Product Details
Catalog Number: MO22119
Applications: WB, IHC, IF
Type: Mouse IgG
Dilutions: ICC 1:2000; IHC 1:2000; WB 1:10,000
Immunogen: Full length recombinant Galectin-3 expressed in and purified from E. coli.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: liquid
Format B: Supernatant
Species Reactivity: Human, Mouse, Rat, Bovine
Entrez: 3958
UniProt: P17931
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$303.00Add to Cart

Galectins are a new family of animal lectins which appear to exhibit a variety of biological functions. Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein.

Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as microglia, dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins making it useful for the study of immune response, diabetes, tumorigenesis and neurogenesis

Images

Rat brain neural cultures stained Galectin-3 (green) and DNA (blue). Staining can be seen in several types of glia and lymphocytic cells, including these cells which have the morphology of microglia. Surrounding cells reveal no Galectin-3 staining. Protocol on data-sheet.

Rat brain neural cultures stained Galectin-3 (green) and DNA (blue). Staining can be seen in several types of glia and lymphocytic cells, including these cells which have the morphology of microglia. Surrounding cells reveal no Galectin-3 staining. Protocol on data-sheet.

Crude HeLa cell extract stained with a panel of monoclonal antibodies to Galectin-3. Lane 12 was probed with the neuromics’ antibody, revealing a band at the expected molecular weight of 30kDa. Protocol on data-sheet.

Crude HeLa cell extract stained with a panel of monoclonal antibodies to Galectin-3. Lane 12 was probed with the neuromics’ antibody, revealing a band at the expected molecular weight of 30kDa. Protocol on data-sheet.

Crude HeLa cell extract stained with a panel of monoclonal antibodies to Galectin-3. Lane 12 was probed with the neuromics’ antibody, revealing a band at the expected molecular weight of 30kDa. Protocol on data-sheet.

Crude HeLa cell extract stained with a panel of monoclonal antibodies to Galectin-3. Lane 12 was probed with the neuromics’ antibody, revealing a band at the expected molecular weight of 30kDa. Protocol on data-sheet.

Questions?
We can help.

We are building our company one satisfied customer at a time. If you have any questions or concerns, please contact us.

Neuromics
5325 West 74th St., Suite 8
Edina, MN 55439

Toll free: 866-350-1500
Int’l phone: 952-374-6161
Fax: 612-677-3976