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| Size | List Price | Price | Cart |
|---|---|---|---|
| 100 ul | $325.00 | Add to Cart |
Fox1 is one of a family of 3 mammalian Fox1 homologues. Fox was discovered in C. elegans as a gene involved in sex determination, and the name Fox is an acronym of "Feminizing locus on X". The Fox protein and its 3 mammalian homologues are all about 46kDa proteins each of which includes a central highly conserved RRM type RNA recognition motif, which corresponds to a small ~70 amino acid structure consisting of 4 beta strands and two alpha-helices. An alternate name for Fox 1 is ataxin-2 binding protein 1 (A2BP1). Like Fox3 (Mouse Monoclonal FOX3 Antibody, MO22122), Fox1 is expressed in neuronal nuclei, but with a different pattern of expression than Fox3. For example, in the cerebellum, Fox3 does not stain Purkinje neurons and Golgi neurons, but these two neuron types are stained by Fox1 antibody |
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Images
Rat brain neural cultures stained with FOX1 (green), and our rabbit polyclonal antibody to NF-M (RA22105, green) and DNA (blue). This antibody reveals nuclear and distal cytoplasmic staining for Fox1, and the complete absence of staining of non-neuronal cells.Protocol on Data-sheet.
Rat brain neural cultures stained with FOX1 (green), and our rabbit polyclonal antibody to NF-M (RA22105, green) and DNA (blue). This antibody reveals nuclear and distal cytoplasmic staining for Fox1, and the complete absence of staining of non-neuronal cells.Protocol on Data-sheet.
Blots of mouse brain homogenates stained with Fox1. Antibody binds closely spaced 48kDa and 46kDa bands. Protocol on Data-sheet.
Blots of mouse brain homogenates stained with Fox1. Antibody binds closely spaced 48kDa and 46kDa bands. Protocol on Data-sheet.