Product Details
Catalog Number: MO22163
Applications: ICC, WB, IHC, IF
Type: Mouse IgG
Immunogen: Full length recombinant human protein
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Chicken, Bovine, Porcine
Entrez: 793
UniProt: P05937
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$325.00Add to Cart

Calbindin, also known as calbindin 1 or calbindin-D28k is a member of the large superfamily of cytoplasmic Ca2+ binding proteins. Calbindin-1 belongs to the subclass of these containing the "EF hand" Ca2+ binding motif originally characterized in parvalbumin. Calbindin is expressed in mammalian brain, intestine, kidney and pancreas. In the brain it is localized in certain classes of neurons, and antibodies to it are useful for identifying specific neuronal cell types. It is particularly concentrated in the dendrites and perikarya of cerebellar Purkinje cells, but is also found in many GABAergic interneurons in the cortex.

Images

Adult mouse cortex (L) and cerebellum (R) sections were stained with MO22163 in red, and co-stained with our rabbit polyclonal anti-Fox3/NeuN antibody (RA22113) in green. Calbindin is expressed in a subset of interneurons in the cortex (L) and prominently expressed in the dendrites of Purkinje cells in the cerebellum molecular layer (R). Blue is Dapi nucleus staining that labels DNA.

Adult mouse cortex (L) and cerebellum (R) sections were stained with MO22163 in red, and co-stained with our rabbit polyclonal anti-Fox3/NeuN antibody (RA22113) in green. Calbindin is expressed in a subset of interneurons in the cortex (L) and prominently expressed in the dendrites of Purkinje cells in the cerebellum molecular layer (R). Blue is Dapi nucleus staining that labels DNA.