Product Details
Catalog Number: MO25036
Applications: WB
Type: Mouse IgG
Immunogen: Full-length recombinant human Caspase 7 protein.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Ascites Fluid
Species Reactivity: Human, Mouse, Rat
Entrez: 840
UniProt: P55210
Downloads: SDS (pdf)
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$275.00Add to Cart

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

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