p21 Antibody detects for the presence or absence of p21 (also known as p21Cip1 , p21Waf1, cyclin-dependent kinase inhibitor 1, or CDK-interacting protein 1) which functions to regulate the cell cycle at G1 through cyclin-CDK2 or cyclin-CDK4 complex inhibition. Decrease expression in p21 is linked to poor prognosis in a number of carcinomas. Normally p21 is expressed in all healthy adult human tissues.
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