Product Details
Catalog Number: MO47051
Applications: IHC, E
Type: Mouse IgG
Dilutions: Immunohistochemistry: 1:1,000-3,000 ELISA: 1:1,000-2,000
Immunogen: Recombinant Human OX40/CD134
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 7293
UniProt: P43489
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$229.00Add to Cart

OX40 or CD134 is encoded by the TNFRSF4 gene, a member of the TNF-receptor superfamily. Expression of OX40 is found in activated CD4 and CD8 T cells, but is absent in resting naϊve T cells and most resting memory T cells. OX40 Antibody detects the presence of OX40, which plays a major role in proliferation and differentiation of naϊve T cells into a population of heterogeneous effector T cells, and has been found to promote proliferation and survival of CD8 T cells. Thus, OX40 and it's ligand, OX40L, is a key player in pathways involving the immune system such as long-term T-cell immunity.

Images
Immunohistochemistry

Immunohistochemistry staining of MO47051 on human tonsil tissue.

Immunohistochemistry

Immunohistochemistry staining of MO47051 on human tonsil tissue.