CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines . CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.
1. CD154-stimulated GM-CSF release by vascular smooth muscle cells elicits monocyte activation-role in atherogenesis. J Mol Med 2007 Jul 10;
- Product Reviews
Leave a review for this product and you could be eligible for a $10 Starbucks gift card.
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products