The term ‘PDGF’ refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets.They act as potent mitogens for almost all mesenchymally-derived cells.
Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist – a short form that is soluble and a long form that is retained by the extracellular matrix..
1. Effects of hyperbaric oxygen and platelet derived growth factor on medial collateral ligament fibroblasts. Undersea Hyperb Med 2007 May-Jun;34(3):181-90.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size PD-ECGF PR15044 10 ug PDGF - A Human PR27059 20 ug PDGF - A Human PR27059 5 ug PDGF - AA Human PR27061 10 ug PDGF - AA Human PR27061 2 ug PDGF - B Human PR27060 20 ug PDGF - B Human PR27060 5 ug PDGF, CF Human PR15024CF 1 ug PDGF, CF Human PR15024CF 5 ug PDGF-BB PR15027 50 ug PDGF-BB, CF PR15026CF 10 ug PDGF-BB, CF PR15026CF 50 ug PDGF-BB, CF PR15027CF 50 ug