Product Details
Catalog Number: PR27174
Type: Protein
Storage: Store at room temperature for up to 3 weeks. Store desiccated at -20°C. Avoid freeze-thaw cycles.
Shipping: Ambient
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
10 ug$205.00Add to Cart

Neurogranin (NRGN) is a calmodulin-binding protein which is expressed solely in the brain, mainly in dendritic spines. NRGN is also taking part in the protein kinase C signaling pathway by being a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. NRGN binds to calmodulin in the absence of calcium. NRGN protein's phosphorylation by protein kinase C lowers its binding ability.

NRGN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (1-78 a.a.) and having a molecular mass of 10.0kDa. NRGN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.


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