ANXA1 is part of the family of Ca(2+)-dependent phospholipid binding proteins which have a Mw between 35kDa-40kDa and are situated on the cytosolic face of the plasma membrane. ANXA1 protein has a Mw of 40kDa, with phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity. Since phospholipase A2 is necessary for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, ANXA1 might have potential anti-inflammatory activity. ANXA1 promotes membrane fusion and iplays a role in exocytosis. The recognition of ANXA1 protein by immunocytochemical leads a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia.
ANXA1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 346 amino acids (1-346 a.a.) and having a molecular mass of 38.7 kDa.
ANXA1 is purified by proprietary chromatographic techniques.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Annexin A10 PR27208 20 ug Annexin A10 PR27208 5 ug Annexin A11 PR27209 20 ug Annexin A11 PR27209 5 ug Annexin A13 PR27210 10 ug Annexin A13 PR27210 2 ug Annexin A2 PR27211 20 ug Annexin A2 PR27211 5 ug Annexin A3 PR27212 20 ug Annexin A3 PR27212 5 ug Annexin A4 PR27213 10 ug Annexin A4 PR27213 2 ug Annexin A5 PR27214 20 ug Annexin A5 PR27214 5 ug Annexin A6 PR27215 10 ug Annexin A6 PR27215 2 ug Annexin A7 PR27216 20 ug Annexin A7 PR27216 5 ug Annexin A8 PR27217 20 ug Annexin A8 PR27217 5 ug Annexin A8 Like-1 PR27218 1 ug Annexin A8 Like-1 PR27218 5 ug