ANXA2 is part of the annexin family and is involved in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein functions as an autocrine factor which increases osteoclast formation and bone resorption. ANXA2 is associated with sickle cell osteonecrosis. Reduced ANXA2 expression is associated with osteosarcoma metastases. ANXA2 is part of the putative cell surface vitamin D binding protein binding site complex and functions to mediate the chemotactic cofactor effect. ANXA2 is involved in dysferlin deficiency and in muscular dystrophies. Human colon adenocarcinoma cell differentiation is related with an up-regulation of ANXA2.
ANXA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 376 amino acids (1-339a.a.) and having a molecular mass of 42.8 kDa. ANXA2 is fused to a 37 amino acid His-Tag at N-Terminus and purified by proprietary chromatographic techniques.
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Name Catalog # Size Annexin A1 PR27207 10 ug Annexin A1 PR27207 2 ug Annexin A10 PR27208 20 ug Annexin A10 PR27208 5 ug Annexin A11 PR27209 20 ug Annexin A11 PR27209 5 ug Annexin A13 PR27210 10 ug Annexin A13 PR27210 2 ug Annexin A3 PR27212 20 ug Annexin A3 PR27212 5 ug Annexin A4 PR27213 10 ug Annexin A4 PR27213 2 ug Annexin A5 PR27214 20 ug Annexin A5 PR27214 5 ug Annexin A6 PR27215 10 ug Annexin A6 PR27215 2 ug Annexin A7 PR27216 20 ug Annexin A7 PR27216 5 ug Annexin A8 PR27217 20 ug Annexin A8 PR27217 5 ug Annexin A8 Like-1 PR27218 1 ug Annexin A8 Like-1 PR27218 5 ug