Product Details
Catalog Number: PR80003
Applications: Cell Assays
Type: Protein
Storage: Store at 4°C short term. Store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Ambient
Format B: lyophilized
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
1 mg$2,475.00Add to Cart
10 ug$105.00Add to Cart
100 ug$405.00Add to Cart

Leukemia Inhibitory Factor (LIF) is a lymphoid factor which promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor-dependent cell lines and promotion of megakaryocyte production in vivo. Mouse LIF is a 20 kDa protein containing 181 amino acid residues.

Our ISOkine™ LIF is produced using barley grain as a bioreactor, and therefore is animal-free, serum-free and endotoxin-free. Furthermore, our unique technology enables us to offer high quality human LIF at much lower prices than the market leaders.

Testimonial: Bioactivity was tested by culturing mouse ES cells either on feeders in complete medium or without feeders in a conditioned medium. In both conditions ISOkine™ LIF was added using concentrations down to 0.1 ng/ml. All concentration conditions resulted in nice looking colonies of pluripotent mouse ES cells. When the ES cells were deprived of LIF they spontaneously differentiated and were able to form embryoid bodies in hanging drops. Dr. Guðrún Valdimarsdóttir, Dept. of Biochemistry and Molecular Biology, Faculty of Medicine, University of Iceland.

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Plant cell system: The barley plant does not contain any pathogens or other components known to be harmful for human or animal stem cells. The plant components are safe and inert. Bioassay analysis and years of successful application in stem cell research verify this further.

Plant cell system: The barley plant does not contain any pathogens or other components known to be harmful for human or animal stem cells. The plant components are safe and inert. Bioassay analysis and years of successful application in stem cell research verify this further.