Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
- Product ReviewsVery good!! Product Name: mGluR6, Rabbit– (Cat# RA13105) http://bit.ly/1fn9Xjp Organization: University of FloridaM - Jul 25, 2014 - Rating: 5.0
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- Sisi Xu, Peijun Zhang, Meng Zhang, Xin Wang, Gang Li, Gezhi Xu, and Yingqin Ni. (2021). Synaptic Changes and the Response of Microglia in a Light-Induced Photoreceptor Degeneration Model. Molecular Vision, 27:206–220.
- Jagadeesh Kumar Venkatesan, Sivaraman Natarajan, Karin Schwarz, Sabine I. Mayer, Kannan Alpadi, Venkat Giri Magupalli, Ching-Hwa Sung, and Frank Schmitz. Nicotinamide Adenine. (2010). Dinucleotide-Dependent Binding of the Neuronal Ca2+ Sensor Protein GCAP2 to Photoreceptor Synaptic Ribbons. J. Neurosci., 30: 6559 - 6576. doi: 10.1523/JNEUROSCI.3701-09.2010
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