P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells.
Please note this is a replacement for RA14012 (whole serum P2Y2 antibody).
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- Oleg Zaika, Jie Zhang, and Mark S. Shapiro. (2011). Functional role of M-type (KCNQ) K+ channels in adrenergic control of cardiomyocyte contraction rate by sympathetic neurons. J. Physiol., 589: 2559 - 2568. doi: 10.1113/jphysiol.2010.204768
- Patrizia Rubini, Javorina Milosevic, Johannes Engelhardt, Mahmoud Al-Khrasani, Heike Franke, Attilla Heinrich, Beata Sperlagh, Sigrid C. Schwarz, Johannes Schwarz, Wolfgang Nörenberg and Peter Illes. (2009). Increase of intracellular Ca2+ by adenine and uracil nucleotides in human midbrain-derived neuronal progenitor cells. Cell Calcium, Volume 45, Issue 5, Pages 485-498. doi: 10.1016/j.ceca.2009.03.008
- Sylvia Sarman, Jorge Mancini, Ingeborg van der Ploeg, J. Oscar Croxatto, Anders Kvanta, Juan E. Gallo. (2008). Involvement of Purinergic P2 Receptors in Experimental Retinal Neovascularization. Current Eye Research, doi: 10.1080/02713680701885470
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