Product Details
Catalog Number: RA14112
Applications: WB, IHC, IF
Type: Rabbit IgG
Immunogen: (C)TDSFSEATNV. Cys added for conjugation to KLH
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Entrez: 18167
UniProt: P97295
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$380.00Add to Cart
50 ul$210.00Add to Cart

Neuropeptide Y (NPY) receptors are members of a G protein-coupled receptor superfamily and they mediate a variety of physiological responses including feeding and vasoconstriction. The endogenous ligands of NPY receptors are a family of structurally related peptides, including NPY, peptide YY (PYY), and pancreatic polypeptide (PP). Increased activity of NPY and its receptors, Y1R, Y2R, and Y5R has been found in the brain in many forms of experimental obesity. Furthermore, several association studies have supported the association between NPY2R and obesity.

This NPY Y2 antibody has been extensively characterized in the spinal cord, brain, and distal colon.

Supporting Products
NameCatalog #Size
NPY Y2 ReceptorP1411250 ul. @ 2 mgs/ml Blocking Peptide
Images
NPY Y2 receptor immunoreactivity in mouse dorsal root ganglion of wild type

NPY Y2 receptor immunoreactivity in mouse dorsal root ganglion of wild type (A) and NPY Y2 receptor Knockout (B) animals. Note that unspecific staining is observed in thick, possibly myelinated fibers. Image courtesy of Dr. Tomas Hökfelt, Karolinska Institute.

NPY Y2 receptor immunoreactivity in mouse dorsal root ganglion of wild type

NPY Y2 receptor immunoreactivity in mouse dorsal root ganglion of wild type (A) and NPY Y2 receptor Knockout (B) animals. Note that unspecific staining is observed in thick, possibly myelinated fibers. Image courtesy of Dr. Tomas Hökfelt, Karolinska Institute.

CCK regulates expression of Y2R in vagal afferent neurons.

CCK regulates expression of Y2R in vagal afferent neurons. The Journal of Neuroscience, November 5, 2008, 28(45):11583-11592; doi:10.1523/JNEUROSCI.2493-08.2008

CCK regulates expression of Y2R in vagal afferent neurons.

CCK regulates expression of Y2R in vagal afferent neurons. The Journal of Neuroscience, November 5, 2008, 28(45):11583-11592; doi:10.1523/JNEUROSCI.2493-08.2008