Product Details
Catalog Number: RA14141
Applications: IHC
Type: Rabbit IgG
Immunogen: SARPDAKEEQQQQLRC
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: liquid
Species Reactivity: Rat
Entrez: 116448
UniProt: Q8TAK6
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$350.00$280.00Add to Cart

Olig1 and Olig2, which have been implicated in oligodendrogenesis, are expressed in the region of the ventral ventricular zone of late embryonic spinal cord where oligodendrocyte progenitors appear. Olig3 is transiently expressed in different types of progenitors of embryonic central nervous system and then disappears in the course of development. In adult, expression of Olig3 is primarily detected in neural tissues.

Olig1  is also strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable

General Reference:

Igor Jakovcevski and Nada Zecevic. Olig Transcription Factors Are Expressed in Oligodendrocyte and Neuronal Cells in Human Fetal CNS. The Journal of Neuroscience, November 2, 2005 25(44):10064 –10073.

Supporting Products
NameCatalog #Size
Olig1P14141100 ul @ 1mg/ml
Images

Immunofluorescence detection of Olig1 in the white matter of adult rat spinal cord using anti-rabbit Cy3-conjugated secondary antibodies (red) and DAPI (blue) as a nuclear counterstain.

Immunofluorescence detection of Olig1 in the white matter of adult rat spinal cord using anti-rabbit Cy3-conjugated secondary antibodies (red) and DAPI (blue) as a nuclear counterstain.