Neurotensin receptor 1 (NTSR1) belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.
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- Thierry Coppola, Sophie Béraud-Dufour, Aurélie Antoine, Jean-Pierre Vincent and Jean Mazella. (2008). Neurotensin protects pancreatic beta cells from apoptosis. The International Journal or Biochemistry & Cell Biology, doi: 10.1016/j.biocel.2008.03.015
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