Product Details
Catalog Number: RA18023
Applications: WB, IHC, IP
Type: Rabbit IgG
Immunogen: Synthetic peptide (KLH-coupled) derived from a sequence of human AP-2alpha.
Storage: Do not aliquot. Store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Primate
Entrez: 7020
UniProt: P05549
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$387.00Add to Cart

The sequence-specific transcription factor activator protein 2α (AP-2α) is required for normal growth and morphogenesis during mammalian development. This includes development of the Neural Crest.

Decreased or loss of AP-2α expression has been observed in many different types of human cancers including breast cancer, ovarian cancer, melanoma and prostate cancer.

Images

AP-2α atining of paraffin-embedded human lung carcinoma

AP-2α atining of paraffin-embedded human lung carcinoma

Western blot analysis of extracts from various cell lines

Western blot analysis of extracts from various cell lines