Product Details
Catalog Number: RA19013
Applications: WB, IHC
Type: Rabbit IgG
Dilutions: IHC 1:1000 WB 1:500-1:1000
Immunogen: Reacts with residues 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 65018
UniProt: Q9BXM7
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$275.00Add to Cart

Mutations in the PTEN-induced kinase (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.

Images

n active lesions PINK1 immunostaining was intense in reactive astrocytes (arrows). Double labeling of PINK1 (green) with the astrocytic marker GFAP (red) demonstrated PINK1 expression in astrocytes (inset).

n active lesions PINK1 immunostaining was intense in reactive astrocytes (arrows). Double labeling of PINK1 (green) with the astrocytic marker GFAP (red) demonstrated PINK1 expression in astrocytes (inset).