The novel BRCAA1 protein’s epitope, SSKKQKRSHK, was mapped to the cytoplasm of MCF7 cells. Immunohistochemistry analysis has shown that the antigen epitope exhibits positive expression in 65% of breast cancer specimens. Its expression is associated with characteristics that are associated with prognosis of breast cancer, and its sera antibody level may be helpful for breast cancer diagnosis.
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- Séverine Landais, Sébastien Landry, Philippe Legault and Eric Rassart. (2007). Oncogenic Potential of the miR-106-363 Cluster and Its Implication in Human T-Cell Leukemia. Cancer Research, 67, 5699-5707. doi: 10.1158/0008-5472.CAN-06-4478
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