Product Details
Catalog Number: RA19036
Applications: WB
Type: Rabbit IgG
Immunogen: Reacts with residues 2-15 [SRRSSRLQAKQQPQC] of the Cyclin E2 protein.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Species Reactivity: Human
Entrez: 9134
UniProt: O96020
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$175.00Add to Cart

Cyclin E2 is a member of the cyclin E family that can associate with and activate Cdk2. Expression of cyclin E2 is essential for the control of the cell cycle at the late G1 and early S phase, and this protein may regulate distinct rate-limiting pathway(s) during this phase . Cyclin E2 specifically interacts with Cdk inhibitors of the CIP/KIP family and activates both Cdk2 and Cdk3. Expression of the viral E6 oncoprotein in normal human fibroblasts increases levels of cyclin E2, but not cyclin E1, while expression of the E7 oncoprotein upregulates both. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.


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