Catalog Number: RA19057
Type: Rabbit IgG
Dilutions: WB 1:500-1:1000
Immunogen: Reacts with residues 515-535 (DKTKKQAVGSPRKIEKELRKS) of the mouse SHPRH protein. 95% sequence identity to rat. 90% sequence identity to human.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse
A novel gene containing SNF2, PHD-finger, RING-finger, helicase, and linker histone domains termed SHPRH, is a possible candidate for a tumor suppressor gene. These domains are characteristic of several DNA repair proteins, transcription factors, and helicases. Mapping of this gene to 6q24, a region reported to contain a tumor suppressor locus suggests a role in tumor suppression.
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