Product Details
Catalog Number: RA20074
Applications: IHC
Type: Rabbit IgG
Immunogen: Synthetic (human) a-MSH coupled to bovine thyroglobulin with glutaraldehyde.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Mouse, Rat, Guinea Pig
Entrez: 5443
UniProt: P01189
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$285.00Add to Cart

The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of peptide hormones that in nature are produced by cells in the intermediate lobe of the pituitary gland. MSH signals to the brain have effects on appetite and sexual arousal.

Most people with primary Addison's have darkening (hyperpigmentation) of the skin, including areas not exposed to the sun; characteristic sites are skin creases (e.g. of the hands), nipple, and the inside of the cheek (buccal mucosa), also old scars may darken. This occurs because melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH, RA21005) share the same precursor molecule, Pro-opiomelanocortin (POMC).

Images
α-MSH staining of rat pituitary gland tissue.

α-MSH staining of rat pituitary gland tissue.

α-MSH staining of rat pituitary gland tissue.

α-MSH staining of rat pituitary gland tissue.