Product Details
Catalog Number: RA20077
Applications: IHC
Type: Rabbit IgG
Immunogen: Synthetic VIP coupled to bovine thyroglobulin (BTg) with carbodiimide (CDI) linker.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Mouse, Rat, Primate, Guinea Pig
Entrez: 7432
UniProt: P01282
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$385.00Add to Cart

Vasoactive Intestinal Peptide (VIP), a 28 amino acid peptide originally isolated from porcine duodenum, is present not only in gastrointestinal tissues but also in neural tissues, possibly as a neurotransmitter, and exhibits a wide variety of biological actions. It belongs to the glucagon family, and in the duodenum is known to stimulate myocardial contractility, cause vasodilation, increase glycogenolysis, lower arterial blood pressure and relax the smooth muscle of trachea, stomach and gall bladder. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. This antibody detects ganglion cells in both the superficial and deep plexus of the wall of the small bowel in human. The VIP producing tumors are usually neuroblastomas of endocrine tumors in the pancreas. It is also a modulator of joint pain.


VIP Staining of rat brain

VIP Staining of rat brain

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