Product Details
Catalog Number: RA21006
Applications: ICC, IHC, IF
Type: Rabbit IgG
Dilutions: Immunohistochemistry: 5-10 ug/ml Immunofluorescence: 5-15 ug/ml
Immunogen: Human Meu-Enkephalin conjugated to BSA.
Storage: The product can be stored as supplied for up to 12 months at 2°C-4°C. After reconstitution, aliquot and store at -20°C for higher stability or at 4°C with an appropriate antibacterial agent. Avoid freeze thaw-cycles.
Shipping: Frozen (Polar Packs)
Format B: lyophilized
Species Reactivity: Human, Mouse, Rat
UniProt: P01189
Downloads: Datasheet (jpg)
Product Sizes
SizeList PricePriceCart
50 ug$185.00Add to Cart

Met-enkephalin is a pentapeptide that appears to enhance immune function at low doses and suppresse at high doses. This molecule acts in the central nervous, neuroendocrine, and immune systems. Cells from these systems have receptors for met-enkephalin and are able to generate met enkephalin from its prohormone, proenkephalin A. Met-enkephalin may be capable of enhancing immune function in cancer or AIDS patients.

It is known to be an endogenous ligand for opioid receptors and acts to mediate analgesia at the spinal level. Met-enkaphalin. Plasma met enkaphalin levels are significantly higher in patients with type I diabetes and could play a role in glucose homeostasis.

Images
Immunohistochemistry

Immunohistochemical detection of Met-Enkephalin in rat spinal cord (central canal) fixed with 4% formaldehyde and cut into 10 μm thick cryostat sections. Tissue was incubated with rabbit polyclonal antibody to Met-Enkephalin at 10 μg/mL overnight at 4°C followed by incubation with Donkey anti-rabbit Rhodamine Red conjugated secondary antibodies at 1:200. Tissue was counterstained with DAPI (blue color) to visualize cell nuclei.

Immunohistochemistry

Immunohistochemical detection of Met-Enkephalin in rat spinal cord (central canal) fixed with 4% formaldehyde and cut into 10 μm thick cryostat sections. Tissue was incubated with rabbit polyclonal antibody to Met-Enkephalin at 10 μg/mL overnight at 4°C followed by incubation with Donkey anti-rabbit Rhodamine Red conjugated secondary antibodies at 1:200. Tissue was counterstained with DAPI (blue color) to visualize cell nuclei.