Product Details
Catalog Number: RA21021
Applications: ICC, WB, IHC, IF
Type: Rabbit IgG
Dilutions: Immunohistochemistry: 5-10 ug/ml Immunofluorescence: 5-15 ug/ml Western Blot: 1 ug/ml
Immunogen: Synthetic peptide
Storage: The product can be stored as supplied for up to 12 months at 2°C-4°C. After reconstitution, aliquot and store at -20°C for higher stability or at 4°C with an appropriate antibacterial agent. Avoid freeze thaw-cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: lyophilized
Species Reactivity: Human
Entrez: 4313
UniProt: P08253
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$235.00Add to Cart

Metalloproteinase 2 is a 72kDa enzyme involved in remodeling of the vasculature, invasion of tumors and degrading extracellular matrix proteins. Its C-terminal does not have a catalytic function and have anti-tumor activity. Cane be detected extracellularly, in cytoplasm and cell nuclei. MMP2 is present in many tumors including breast and prostate cancer.

Images
Immunohistochemistry

Immunohistochemical detection of MMP2 in formalin fixed human prostate cancer. 10 μm paraffin-embedded tissue sections were incubated with rabbit polyclonal antibody to MMP2 at 6 μg/mL overnight at 4°C followed by HRP/AEC detection (red) and counterstaining with hematoxylin (blue).

Immunohistochemistry

Immunohistochemical detection of MMP2 in formalin fixed human prostate cancer. 10 μm paraffin-embedded tissue sections were incubated with rabbit polyclonal antibody to MMP2 at 6 μg/mL overnight at 4°C followed by HRP/AEC detection (red) and counterstaining with hematoxylin (blue).