Product Details
Catalog Number: RA24427
Applications: IHC, IF
Type: Rabbit IgG
Immunogen: Calbindin D -28K purified from bovine cerebellum
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Mouse, Rat
Entrez: 793
UniProt: P05937
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$375.00Add to Cart

Calbindin-D, also known as Calbindin 1, is a Vitamin D-dependent cytoplasmic protein in the EF-hand calcium binding protein family that includes calmodulin, parvalbumin, troponin C, and S100. Calbindin-D is widely expressed and regulates calcium homeostasis. Calbindin-D protects neurons from excitotoxic and apoptotic cell death by buffering excess calcium. Human, mouse, and rat Calbindin-D share 99% amino acid sequence identity

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Images
IHC image of neurons staining for the calbindin in the rat cortex.

IHC image of neurons staining for the calbindin in the rat cortex. The tissue was fixed with 4% formaldehyde in 0.1 M phosphate buffer, before being removed and prepared for vibratome sectioning.

IHC image of neurons staining for the calbindin in the rat cortex.

IHC image of neurons staining for the calbindin in the rat cortex. The tissue was fixed with 4% formaldehyde in 0.1 M phosphate buffer, before being removed and prepared for vibratome sectioning.