Regulation of gene expression of dopamine beta hydroxylase (DBH) and tyrosine hydroxylase (TH), two of the catecholamine biosynthetic enzymes, by cyclic AMP, diacyl glycerol, and Ca2+ leads to increased neurotransmitter biosynthesis.
Dopamine beta-hydroxylase catalyzes the conversion of dopamine to noradrenaline and is expressed selectively in noradrenergic and adrenergic neurons in the nervous system. The disruption of the DBH gene is thought to cause changes in development and behavior in certain models. Both DBH and the multiple regulatory pathways of DBH are of increasing research in many neurological diseases.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email firstname.lastname@example.org, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size DOPA decarboxylase RA25065 100 ul phospho-Tyrosine Hydroxylase (Ser40) RA18026 100 ul Tyrosine Hydroxylase CH22122 100 ul Tyrosine Hydroxylase MO20001 100 ul Tyrosine Hydroxylase MO22186 100 ul Tyrosine Hydroxylase MO22941 100 ul Tyrosine Hydroxylase RA21030 50 ug Tyrosine Hydroxylase RA22135 100 ul Tyrosine Hydroxylase SO25000 100 ul